雷暴哮喘:当前观点和新趋势。

IF 8.2 1区 医学 Q1 ALLERGY
Francis Thien, Janet M Davies, Jo A Douglass, Mark Hew
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引用次数: 0

摘要

雷暴哮喘的孤立发作和流行病暴发已有40多年的记录,其全球地理范围遍及欧洲、北美、中东、亚洲、大洋洲和非洲。这种现象包括特定的环境和气象因素,与空气过敏原的传播和暴露在易感过敏原敏感的个人和人群中相互作用。气候变化可能会导致花粉过敏季节延长,加上花粉过敏原性增加,以及极端天气事件的可能性增加。不同人群对雷暴哮喘的表现、住院治疗和死亡的易感性不同,某些种族群体的易感性增加,表明基因-环境相互作用。本临床评论综述了雷暴哮喘的特点和最新的流行病学;检查空气生物学和气候变化的作用;讨论急诊、住院和死亡的危险因素;考虑雷暴哮喘的最新研究和预测因素,并提出管理和减轻风险的策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thunderstorm asthma: current perspectives and emerging trends.

Isolated episodes and epidemic outbreaks of thunderstorm asthma have now been documented for over 40 years, with global geographical reach across Europe, North America, Middle East, Asia, Oceania and Africa. This phenomenon encompasses specific environmental and meteorological factors, interacting with aeroallergen propagation and exposure in susceptible allergen-sensitized individuals and populations. There is a likely contribution from climate change with prolonged allergenic pollen seasons combined with increased pollen allergenicity, as well as heightened likelihood of extreme weather events. Differential population susceptibility to thunderstorm asthma presentations, hospitalizations and deaths with increased vulnerability of certain ethnic groups suggest a gene-environment interaction. This Clinical Commentary reviews the characteristics and updates the epidemiology of thunderstorm asthma; examines the role of aerobiology and climate change; discusses risk factors for emergency presentations, hospital admissions and deaths; considers latest research and predictors of thunderstorm asthma, and proposes strategies to manage and mitigate risk.

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来源期刊
CiteScore
11.10
自引率
9.60%
发文量
683
审稿时长
50 days
期刊介绍: JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.
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