慕尼黑骨骼肌减少症登记处(MUSAR):为提高知名度,更频繁的诊断和创新的新治疗铺平道路。

IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY
Olivia Tausendfreund, Uta Ferrari, Christopher Held, Sebastian Martini, Katharina Mueller, Hannah Reif, Michaela Rippl, Sabine Schluessel, Ralf Schmidmaier, Michael Drey
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引用次数: 0

摘要

背景:肌少症的共识定义使诊断算法清晰。该综合征现在也可以在德国进行编码(国际疾病分类10,ICD-10 GM 62.50)。与估计的患病率相比,它仍然严重未被诊断。目前的治疗选择包括抗阻训练和富含蛋白质的饮食,而药物选择仍然缺失。目的:慕尼黑骨骼肌减少症登记处(MUSAR)旨在提高对该综合征和受影响个体的认识。此外,它还寻求深入了解风险因素、原因和治疗方法。本出版物对90例不同程度肌肉减少症患者数据集进行了初步分析,并检查了关键的老年参数队列。材料和方法:自2018年以来,来自慕尼黑路德维希马克西米利安大学老年诊所的患者已经能够将他们的数据贡献给登记处。社会人口学、人体测量学、功能和实验室数据收集在一个基于网络的注册表中。结果:与无肌少症患者相比,肌少症患者明显年龄大,合并症多,功能表现差,生活质量下降。讨论:这些结果强调了进一步研究和开发新形式治疗的迫切需要,以改善这些患者的生活质量和独立性。招聘困难等挑战使这一努力复杂化。MUSAR旨在最大限度地减少这些问题,并通过系统收集住院期间的患者数据,为生成广泛的数据提供宝贵的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The MUnich SArcopenia Registry (MUSAR) : Paving the way for increased visibility, more frequent diagnoses and innovative new treatment.

The MUnich SArcopenia Registry (MUSAR) : Paving the way for increased visibility, more frequent diagnoses and innovative new treatment.

The MUnich SArcopenia Registry (MUSAR) : Paving the way for increased visibility, more frequent diagnoses and innovative new treatment.

Background: The consensus definition of sarcopenia enables a clear diagnostic algorithm. The syndrome can now also be coded in Germany (International Classification of Diseases 10, ICD-10 GM 62.50). Compared to the estimated prevalence it is still significantly underdiagnosed. Current treatment options include resistance training and a protein-rich diet, while pharmacological options are still missing.

Objective: The Munich Sarcopenia Registry (MUSAR) aims to raise awareness of the syndrome and affected individuals. Additionally, it seeks to gain insights into risk factors, causes and treatment approaches. This publication conducts an initial analysis of 90 patient datasets with varying degrees of sarcopenia and examines the cohort for key geriatric parameters.

Material and methods: Since 2018 patients from the geriatric clinic of the Ludwig Maximilians University Munich have been able to contribute their data to the registry. Sociodemographic, anthropometric, functional, and laboratory data are collected in a web-based registry.

Results: Compared to patients without sarcopenia, patients with sarcopenia are significantly older, have more comorbidities and show poorer functional performance as well as reduced quality of life.

Discussion: The results highlight the urgent need for further research and the development of new forms of treatment to improve the quality of life and independence of these patients. Challenges such as difficult recruitment complicate this endeavor. The MUSAR aims to minimize these issues and provides a valuable basis for generating extensive data through the systematic collection of patient data during hospital stays.

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来源期刊
CiteScore
2.00
自引率
16.70%
发文量
126
审稿时长
6-12 weeks
期刊介绍: The fact that more and more people are becoming older and are having a significant influence on our society is due to intensive geriatric research and geriatric medicine in the past and present. The Zeitschrift für Gerontologie und Geriatrie has contributed to this area for many years by informing a broad spectrum of interested readers about various developments in gerontology research. Special issues focus on all questions concerning gerontology, biology and basic research of aging, geriatric research, psychology and sociology as well as practical aspects of geriatric care. Target group: Geriatricians, social gerontologists, geriatric psychologists, geriatric psychiatrists, nurses/caregivers, nurse researchers, biogerontologists in geriatric wards/clinics, gerontological institutes, and institutions of teaching and further or continuing education.
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