[阿片类镇痛药的临床药理学]。

IF 1.1 4区医学 Q3 ANESTHESIOLOGY

Schmerz Pub Date : 2025-04-09 DOI:10.1007/s00482-025-00880-y

Constanze Rémi, Jennifer Berner, Aleksandra Dukic-Ott, Christina Hepperle

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引用次数: 0

摘要

阿片类药物是必不可少的镇痛药物，也是多种药物的一部分。内源性阿片系统及其受体的研究有助于更好地了解阿片系统的优缺点，并为优化新物质提供可能性。与不同阿片受体的相互作用和非阿片效应是治疗设计中越来越需要考虑的重要方面，以确保安全有效的疼痛管理。

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[Clinical pharmacology of opioid analgesics].

Opioids are essential for analgesia and part of a multifarious group of drugs. The study of the endogenous opioid system and its receptors contributes to a better understanding of the advantages and disadvantages of opioids and to develop possibilities for optimization of new substances. Interactions with the different opioid receptors and the non-opioid effects are important aspects that increasingly need to be considered in the treatment design to ensure safe and effective pain management.

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来源期刊

Schmerz 医学-临床神经学

CiteScore

2.00

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Der Schmerz is an internationally recognized journal and addresses all scientists, practitioners and psychologists, dealing with the treatment of pain patients or working in pain research. The aim of the journal is to enhance the treatment of pain patients in the long run. Review articles provide an overview on selected topics and offer the reader a summary of current findings from all fields of pain research, pain management and pain symptom management. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.