益生菌和益生元：治疗口腔潜在恶性疾病和胃肠道癌前病变的新策略。

IF 7.8 1区生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

npj Biofilms and Microbiomes Pub Date : 2025-04-08 DOI:10.1038/s41522-025-00688-9

Zhuwei Huang, Jiaye Zhu, Xiangwen Bu, Shulai Lu, Yixian Luo, Ting Liu, Ning Duan, Wenmei Wang, Yong Wang, Xiang Wang

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引用次数: 0

摘要

口腔潜在恶性疾病（OPMDs）和胃肠道癌前病变（GPLs）是主要的公共卫生问题，因为它们有可能发展为癌症。益生菌、益生元和工程益生菌对opmd和gpl的预防和管理有积极的影响。本文旨在全面综述益生菌、益生元和工程益生菌在opmd和gpl中的应用现状，探讨其潜在的作用机制，并对其未来的临床应用进行展望。

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Probiotics and prebiotics: new treatment strategies for oral potentially malignant disorders and gastrointestinal precancerous lesions.

Oral potentially malignant disorders (OPMDs) and gastrointestinal precancerous lesions (GPLs) are major public health concerns because of their potential to progress to cancer. Probiotics, prebiotics, and engineered probiotics can positively influence the prevention and management of OPMDs and GPLs. This review aims to comprehensively review the application status of probiotics, prebiotics and engineered probiotics in OPMDs and GPLs, explore their potential mechanisms of action, and anticipate their future clinical use.

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来源期刊

npj Biofilms and Microbiomes Immunology and Microbiology-Microbiology

CiteScore

12.10

自引率

3.30%

发文量

审稿时长

9 weeks

期刊介绍： npj Biofilms and Microbiomes is a comprehensive platform that promotes research on biofilms and microbiomes across various scientific disciplines. The journal facilitates cross-disciplinary discussions to enhance our understanding of the biology, ecology, and communal functions of biofilms, populations, and communities. It also focuses on applications in the medical, environmental, and engineering domains. The scope of the journal encompasses all aspects of the field, ranging from cell-cell communication and single cell interactions to the microbiomes of humans, animals, plants, and natural and built environments. The journal also welcomes research on the virome, phageome, mycome, and fungome. It publishes both applied science and theoretical work. As an open access and interdisciplinary journal, its primary goal is to publish significant scientific advancements in microbial biofilms and microbiomes. The journal enables discussions that span multiple disciplines and contributes to our understanding of the social behavior of microbial biofilm populations and communities, and their impact on life, human health, and the environment.