植入物的设计及其在骨质疏松骨固定中的应用:钉子、钢板和外固定架的新技术。

IF 1.1 4区 医学 Q3 ORTHOPEDICS
Indian Journal of Orthopaedics Pub Date : 2024-12-02 eCollection Date: 2025-03-01 DOI:10.1007/s43465-024-01295-0
Srinivas B S Kambhampati, Senthilvelan Rajagopalan, Vineet Thomas Abraham, Murali Poduval, Lalit Maini
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引用次数: 0

摘要

背景:骨质疏松症以骨量减少和骨组织退化为特征,是一个主要的全球健康问题,特别是对老龄化人口而言。由于骨质疏松症的骨质密度和强度降低,传统的固定技术常常失败。骨科植入物的技术进步,特别是钉子、钢板和外固定架,已经出现以应对这些挑战。材料和方法:植入体设计的改进主要集中在材料特性、表面修饰和几何形状的改进上。钛及其合金具有较低的弹性模量和较高的强度重量比等生物力学特性。聚乳酸和镁合金等可生物降解材料在骨骼愈合过程中具有逐渐吸收的优点。表面修饰,如生物活性材料涂层和药物洗脱表面,促进骨整合并增强固定强度。结果和讨论:髓内钉(IM)已经发展到提高稳定性和减少骨质疏松性骨折的并发症。第三代和第四代指甲结合表面处理,以更好地融合和愈合。螺钉设计、锁定机制和柔性轴向刺激的进步改善了固定和允许微运动,促进了骨折愈合。使用外固定架,特别是对于骨质疏松的复杂骨折,提供了侵入性较小的治疗选择,具有适应性刚度,可改善愈合。结论:种植体材料、设计和手术技术的技术创新显著改善了骨质疏松性骨折的治疗。包括3D打印、虚拟和增强现实以及人工智能在内的新技术在增强植入物定制、手术计划和术后结果方面显示出了希望。然而,为了扩大其临床应用,还需要进一步的临床验证和研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Implant Design and Its Applications in the Fixation of Osteoporotic Bones: Newer Technologies in Nails, Plates and External Fixators.

Background: Osteoporosis, characterised by decreased bone mass and degradation of bone tissue, poses a major global health concern, particularly for the ageing population. The traditional fixation techniques often fail in osteoporotic bones due to their diminished density and strength. Technological advancements in orthopaedic implants, specifically nails, plates, and external fixators, have emerged to address these challenges.

Materials and methods: Improvements in implant design focus on material properties, surface modifications, and geometric advancements. Titanium and its alloys are favoured for their biomechanical properties such as lower elastic modulus and high strength-to-weight ratio. The biodegradable materials like polylactic acid and magnesium alloys offer the advantage of gradual resorption as bone heals. Surface modifications, such as coatings with bioactive materials and drug-eluting surfaces, promote osseointegration and enhance fixation strength.

Results and discussion: Intramedullary (IM) nails have evolved to enhance stability and minimise complications associated with osteoporotic fractures. Third and fourth-generation nails incorporate surface treatments for better integration and healing. The advances in screw design, locking mechanisms, and flexible axial stimulation have improved fixation and allowed micromotion, which promotes fracture healing. The use of external fixators, particularly for complex fractures in osteoporotic bones, offers less invasive treatment options with adaptable stiffness for improved healing.

Conclusion: Technological innovations in implant materials, design, and surgical techniques have significantly improved the management of osteoporotic fractures. Newer technologies, including 3D printing, virtual and augmented reality, and artificial intelligence, show promise in enhancing implant customization, surgical planning, and postoperative outcomes. However, further clinical validation and research are needed to expand their clinical applications.

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来源期刊
CiteScore
1.80
自引率
0.00%
发文量
185
审稿时长
9 months
期刊介绍: IJO welcomes articles that contribute to Orthopaedic knowledge from India and overseas. We publish articles dealing with clinical orthopaedics and basic research in orthopaedic surgery. Articles are accepted only for exclusive publication in the Indian Journal of Orthopaedics. Previously published articles, articles which are in peer-reviewed electronic publications in other journals, are not accepted by the Journal. Published articles and illustrations become the property of the Journal. The copyright remains with the journal. Studies must be carried out in accordance with World Medical Association Declaration of Helsinki.
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