人工孢子层状纳米壳形成过程中磷酸钙的超快、细胞相容矿化。

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-04-09 DOI:10.1039/d5cc00522a

Duc Tai Nguyen , Sang Yeong Han , Hyunwoo Choi , Nayoung Kim , Gulaim A. Seisenbaeva , Vadim G. Kessler , Insung S. Choi

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引用次数: 0

摘要

纳米壳中催化酶的空间控制限制在生物反应器、合成细胞和人工孢子中具有巨大的应用潜力。无定形磷酸钙（CaP）前体的利用使酿酒酵母细胞以细胞兼容的方式被酶包埋的多层CaP纳米壳纳米封装，为活细胞与功能实体在空间控制配置中连接提供了一种先进的化学工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Ultrafast, cytocompatible mineralization of calcium phosphate in the formation of stratified nanoshells of artificial spores†

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Ultrafast, cytocompatible mineralization of calcium phosphate in the formation of stratified nanoshells of artificial spores†

Spatially controlled confinement of catalytic enzymes within nanoshells holds substantial potential for applications in bioreactors, synthetic cells, and artificial spores. The utilization of amorphous calcium phosphate (CaP) precursors enables the extremely rapid (<5 seconds) construction of thick (∼400 nm) CaP nanoshells, stratified with distinct enzymes, on various tannic acid-primed substrates. Saccharomyces cerevisiae cells are nanoencapsulated with enzyme-embedded, multilayered CaP nanoshells in a cytocompatible manner, providing an advanced chemical tool for interfacing living cells with functional entities in a spatially controlled configuration.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.