Yindong Liu, Mengyao Guo, Xiaoding Liu, Huanwen Wu, Yan Jiang, Zhiwei Wang, Hongli Jing, Weibo Xia, Jizhi Zhao, Lian Zhou
{"title":"冷冻消融成功治疗颌骨磷化间充质肿瘤致肿瘤性骨软化1例","authors":"Yindong Liu, Mengyao Guo, Xiaoding Liu, Huanwen Wu, Yan Jiang, Zhiwei Wang, Hongli Jing, Weibo Xia, Jizhi Zhao, Lian Zhou","doi":"10.1007/s11657-025-01525-4","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>A 35-year-old man was diagnosed with tumor-induced osteomalacia (TIO) caused by a phosphaturic mesenchymal tumor (PMT) in the right maxilla.</p><h3>Case Summary</h3><p>The patient underwent CT-guided cryoablation at our institution, which successfully eradicated the tumor while preserving the pulpal vitality of adjacent teeth. We describe the clinical history, physical examination findings, laboratory tests, functional imaging, and follow-up protocol for evaluating treatment outcomes. Cryoablation demonstrated therapeutic efficacy through symptomatic relief, normalization of serum phosphorus levels, and maintenance of pulpal vitality, as well as preservation of neighboring natural teeth.</p><h3>Conclusion</h3><p>Although extensive surgical resection remains the standard treatment for PMTs in jaw bones, image-guided cryoablation presents a minimally invasive alternative. This approach offers significant advantages in preserving occlusal anatomy and functionality, marking a paradigm shift in TIO management.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Successful cryoablation for a phosphaturic mesenchymal tumor in the maxilla causing tumor-induced osteomalacia: a case report\",\"authors\":\"Yindong Liu, Mengyao Guo, Xiaoding Liu, Huanwen Wu, Yan Jiang, Zhiwei Wang, Hongli Jing, Weibo Xia, Jizhi Zhao, Lian Zhou\",\"doi\":\"10.1007/s11657-025-01525-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>A 35-year-old man was diagnosed with tumor-induced osteomalacia (TIO) caused by a phosphaturic mesenchymal tumor (PMT) in the right maxilla.</p><h3>Case Summary</h3><p>The patient underwent CT-guided cryoablation at our institution, which successfully eradicated the tumor while preserving the pulpal vitality of adjacent teeth. We describe the clinical history, physical examination findings, laboratory tests, functional imaging, and follow-up protocol for evaluating treatment outcomes. Cryoablation demonstrated therapeutic efficacy through symptomatic relief, normalization of serum phosphorus levels, and maintenance of pulpal vitality, as well as preservation of neighboring natural teeth.</p><h3>Conclusion</h3><p>Although extensive surgical resection remains the standard treatment for PMTs in jaw bones, image-guided cryoablation presents a minimally invasive alternative. This approach offers significant advantages in preserving occlusal anatomy and functionality, marking a paradigm shift in TIO management.</p></div>\",\"PeriodicalId\":8283,\"journal\":{\"name\":\"Archives of Osteoporosis\",\"volume\":\"20 1\",\"pages\":\"\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-04-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Osteoporosis\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11657-025-01525-4\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Osteoporosis","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s11657-025-01525-4","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Successful cryoablation for a phosphaturic mesenchymal tumor in the maxilla causing tumor-induced osteomalacia: a case report
Background
A 35-year-old man was diagnosed with tumor-induced osteomalacia (TIO) caused by a phosphaturic mesenchymal tumor (PMT) in the right maxilla.
Case Summary
The patient underwent CT-guided cryoablation at our institution, which successfully eradicated the tumor while preserving the pulpal vitality of adjacent teeth. We describe the clinical history, physical examination findings, laboratory tests, functional imaging, and follow-up protocol for evaluating treatment outcomes. Cryoablation demonstrated therapeutic efficacy through symptomatic relief, normalization of serum phosphorus levels, and maintenance of pulpal vitality, as well as preservation of neighboring natural teeth.
Conclusion
Although extensive surgical resection remains the standard treatment for PMTs in jaw bones, image-guided cryoablation presents a minimally invasive alternative. This approach offers significant advantages in preserving occlusal anatomy and functionality, marking a paradigm shift in TIO management.
期刊介绍：
Archives of Osteoporosis is an international multidisciplinary journal which is a joint initiative of the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA. The journal will highlight the specificities of different regions around the world concerning epidemiology, reference values for bone density and bone metabolism, as well as clinical aspects of osteoporosis and other bone diseases.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
