Both humans and animals use water for a variety of functions. However, access to drinking water and agricultural water continues to be a major problem in many areas, especially Southwest Nigeria. Based on sodium adsorption ratio (SAR), soluble sodium percentage (SSP), magnesium adsorption ratio (MAR), and exchangeable sodium percentage (ESP), this study is unique because it offers a thorough evaluation of the metal (Na, Ca, K, Mg, Cr, Mn, Cu, Pb, Cd, and Fe) levels in water samples from thirty-five (35) sites in Osun, Ondo, and Ekiti States with a range of socioeconomic activities and environmental conditions. This study’s main goal is to evaluate the metal concentrations in the water samples and decide whether or not they are suitable for irrigation. Water samples were taken from rivers and streams (10), boreholes (8), wells (15), and rain (2). Atomic Absorption Spectroscopy (AAS) was used to determine the metal content of the samples. The mean concentration of the metals showed the following results: Ca > K > Na > Mg > Fe > Mn > Cr > Cu > Pb > Cd. The irrigation assessments yielded the following results: ESP (10.32), KR (0.50), MAR (17.84), SAR (8.69), and SSP (22.85). Comparing the findings of this investigation, it was found that K, Mg, Na, Ca, Pb, and Cr were below the national limit, while Cu, Cd, and Fe were marginally above the National Environmental Standards and Regulations Enforcement Agency (NESREA) limits. Similarly, it was found that the acceptable limits were exceeded by Mn, Pb, Cd, and Cr, but the limits for Na and Cu were below the World Health Organization (WHO) level. The different activities that took place in the studied locations maybe the causes of the higher levels. The irrigation water samples are safe and of high quality. According to the study’s findings, heavy metal contamination of water samples is a widespread problem in Southwest Nigeria that poses major dangers to public health. In order to guarantee safe irrigation and drinking water, the results highlight the necessity of frequent water quality monitoring, public awareness initiatives, and the adoption of stronger laws.