S D Israel, A Del Cañizo, S Monje, M Sáenz, J Bueno, J Ordóñez, L Pérez Egido, M A García Casillas, J A Cerdá, I Bada Bosch, M Fanjul, D Peláez, J C de Agustín
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Gastrointestinal stromal tumor surgery in pediatrics.
Introduction: Gastrointestinal stromal tumors (GIST) are infrequent in pediatric patients. The management of metastatic and irresectable tumors is usually non-surgical, with tyrosine-kinase inhibitors being the treatment of choice.
Clinical case: We present the case of a 14-year-old female patient with a metastatic and irresectable GIST treated with sunitinib that required surgery as a result of severe hemoperitoneum episodes with anemia and hemodynamic instability. A cytoreductive surgery with R2 resection margins was carried out. After a 10-year follow-up period, the patient remains under oncological treatment.
Discussion: The treatment of metastatic and irresectable GIST consists of tyrosine-kinase inhibitors. Evidence regarding the role of surgery remains limited, which means extreme caution should be exerted when indicating surgical treatment. However, surgery is still a useful tool within the array of therapeutic options.
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