Zhanyu Su, Shanshan Wang, Siya Li, Ruiwen Wang, Yaxin Li, Shuli Di, Yaqian Xu, Jinwei Hu, Julio Ortega-Usobiaga, Zheng Wang, Ming X Wang, Kangjun Li
{"title":"低前房深度眼植入V4c晶体后前段特征的改变：光学相干断层成像研究。","authors":"Zhanyu Su, Shanshan Wang, Siya Li, Ruiwen Wang, Yaxin Li, Shuli Di, Yaqian Xu, Jinwei Hu, Julio Ortega-Usobiaga, Zheng Wang, Ming X Wang, Kangjun Li","doi":"10.3928/1081597X-20250225-01","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To investigate anterior segment changes after implantable collamer lens V4c (ICL-V4c; STAAR Surgical) implantation in eyes with low anterior chamber depth (ACD) and compare them with eyes with normal ACD.</p><p><strong>Methods: </strong>This prospective, interventional case-control study included 96 eyes of 48 patients with a low ACD (< 2.8 mm) and 44 eyes of 22 patients with normal ACD (≥ 2.8 mm) receiving a 12.1-mm ICL. All patients underwent follow-up and comprehensive ophthalmic examinations preoperatively and at 1, 3, and 6 months after surgery. Anterior segment parameters, including ACD, anterior chamber width, crystalline lens rise, anterior chamber angle, trabecular-iris angle (TIA), angle opening distance, trabecular-iris space area, the distance from cornea to ICL, and vault were all conducted by optical coherence tomography. These parameters from the last follow-up (6 months postoperatively) were used for statistical analysis to assess changes in anterior segment structure and their relationship with vault height.</p><p><strong>Results: </strong>The mean safety and efficacy index in eyes with low ACD were 1.23 ± 0.22 and 1.21 ± 0.08 respectively. In both groups, anterior chamber structure parameters become narrower compared to preoperatively (all <i>P</i> < .05). Preoperative ACD and C-ICL demonstrated significant correlations with ICL vault in eyes with low ACD (<i>P</i> < .001). Compared with eyes with normal ACD preoperatively, eyes with low ACD are more prone to have low vault (<i>P</i> < .01). There is a correlation between normal vault and corneal horizontal white-to-white distance (<i>P</i> = .032), ACD (<i>P</i> = .046), and temporal TIA<sub>500</sub> (<i>P</i> = .016).</p><p><strong>Conclusions: </strong>ICL-V4c surgery in eyes with low ACD is safe and efficacious. In patients with low ACD, the normal vault could be better anticipated by considering preoperative anterior chamber angle, white-to-white distance, and ACD. <b>[<i>J Refract Surg</i>. 2025;41(4):e342-e355.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 4","pages":"e342-e355"},"PeriodicalIF":2.9000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anterior Segment Characteristics Changes After Implantable Collamer Lens V4c in Low Anterior Chamber Depth Eyes: An Optical Coherence Tomography Study.\",\"authors\":\"Zhanyu Su, Shanshan Wang, Siya Li, Ruiwen Wang, Yaxin Li, Shuli Di, Yaqian Xu, Jinwei Hu, Julio Ortega-Usobiaga, Zheng Wang, Ming X Wang, Kangjun Li\",\"doi\":\"10.3928/1081597X-20250225-01\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To investigate anterior segment changes after implantable collamer lens V4c (ICL-V4c; STAAR Surgical) implantation in eyes with low anterior chamber depth (ACD) and compare them with eyes with normal ACD.</p><p><strong>Methods: </strong>This prospective, interventional case-control study included 96 eyes of 48 patients with a low ACD (< 2.8 mm) and 44 eyes of 22 patients with normal ACD (≥ 2.8 mm) receiving a 12.1-mm ICL. All patients underwent follow-up and comprehensive ophthalmic examinations preoperatively and at 1, 3, and 6 months after surgery. Anterior segment parameters, including ACD, anterior chamber width, crystalline lens rise, anterior chamber angle, trabecular-iris angle (TIA), angle opening distance, trabecular-iris space area, the distance from cornea to ICL, and vault were all conducted by optical coherence tomography. These parameters from the last follow-up (6 months postoperatively) were used for statistical analysis to assess changes in anterior segment structure and their relationship with vault height.</p><p><strong>Results: </strong>The mean safety and efficacy index in eyes with low ACD were 1.23 ± 0.22 and 1.21 ± 0.08 respectively. In both groups, anterior chamber structure parameters become narrower compared to preoperatively (all <i>P</i> < .05). Preoperative ACD and C-ICL demonstrated significant correlations with ICL vault in eyes with low ACD (<i>P</i> < .001). Compared with eyes with normal ACD preoperatively, eyes with low ACD are more prone to have low vault (<i>P</i> < .01). There is a correlation between normal vault and corneal horizontal white-to-white distance (<i>P</i> = .032), ACD (<i>P</i> = .046), and temporal TIA<sub>500</sub> (<i>P</i> = .016).</p><p><strong>Conclusions: </strong>ICL-V4c surgery in eyes with low ACD is safe and efficacious. In patients with low ACD, the normal vault could be better anticipated by considering preoperative anterior chamber angle, white-to-white distance, and ACD. <b>[<i>J Refract Surg</i>. 2025;41(4):e342-e355.]</b>.</p>\",\"PeriodicalId\":16951,\"journal\":{\"name\":\"Journal of refractive surgery\",\"volume\":\"41 4\",\"pages\":\"e342-e355\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of refractive surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3928/1081597X-20250225-01\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of refractive surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3928/1081597X-20250225-01","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Anterior Segment Characteristics Changes After Implantable Collamer Lens V4c in Low Anterior Chamber Depth Eyes: An Optical Coherence Tomography Study.
Purpose: To investigate anterior segment changes after implantable collamer lens V4c (ICL-V4c; STAAR Surgical) implantation in eyes with low anterior chamber depth (ACD) and compare them with eyes with normal ACD.
Methods: This prospective, interventional case-control study included 96 eyes of 48 patients with a low ACD (< 2.8 mm) and 44 eyes of 22 patients with normal ACD (≥ 2.8 mm) receiving a 12.1-mm ICL. All patients underwent follow-up and comprehensive ophthalmic examinations preoperatively and at 1, 3, and 6 months after surgery. Anterior segment parameters, including ACD, anterior chamber width, crystalline lens rise, anterior chamber angle, trabecular-iris angle (TIA), angle opening distance, trabecular-iris space area, the distance from cornea to ICL, and vault were all conducted by optical coherence tomography. These parameters from the last follow-up (6 months postoperatively) were used for statistical analysis to assess changes in anterior segment structure and their relationship with vault height.
Results: The mean safety and efficacy index in eyes with low ACD were 1.23 ± 0.22 and 1.21 ± 0.08 respectively. In both groups, anterior chamber structure parameters become narrower compared to preoperatively (all P < .05). Preoperative ACD and C-ICL demonstrated significant correlations with ICL vault in eyes with low ACD (P < .001). Compared with eyes with normal ACD preoperatively, eyes with low ACD are more prone to have low vault (P < .01). There is a correlation between normal vault and corneal horizontal white-to-white distance (P = .032), ACD (P = .046), and temporal TIA500 (P = .016).
Conclusions: ICL-V4c surgery in eyes with low ACD is safe and efficacious. In patients with low ACD, the normal vault could be better anticipated by considering preoperative anterior chamber angle, white-to-white distance, and ACD. [J Refract Surg. 2025;41(4):e342-e355.].
期刊介绍：
The Journal of Refractive Surgery, the official journal of the International Society of Refractive Surgery, a partner of the American Academy of Ophthalmology, has been a monthly peer-reviewed forum for original research, review, and evaluation of refractive and lens-based surgical procedures for more than 30 years. Practical, clinically valuable articles provide readers with the most up-to-date information regarding advances in the field of refractive surgery. Begin to explore the Journal and all of its great benefits such as:
• Columns including “Translational Science,” “Surgical Techniques,” and “Biomechanics”
• Supplemental videos and materials available for many articles
• Access to current articles, as well as several years of archived content
• Articles posted online just 2 months after acceptance.
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