[原位心脏移植术后随访中三尖瓣功能不全的机制]。

IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Medicina-buenos Aires Pub Date : 2025-01-01
Pilar Domenech, Estefanía Mestrallet, Ricardo Posatini, César Belziti, Rodolfo Pizarro
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引用次数: 0

摘要

三尖瓣反流(TR)是心脏移植术后最常见的瓣膜病,发生率为19% ~ 84%。严重程度随随访而增加。目的是描述移植后tr发展的机制。材料和方法:单中心,回顾性队列研究,包括2012年至2022年间接受原位心脏移植的患者。分别于移植后6、12、18个月进行超声心动图检查。三尖瓣反流的机制描述为心房扩张或双心房技术,多次心内膜活检,右心室扩张和功能障碍,既往肺动脉高压和受体腔与移植器官不匹配。结果:共纳入234例患者。移植后6个月显著三尖瓣反流发生率为12.8%。右室扩张和功能障碍是最常见的机制,67%,错配17%,器质性瓣膜病变和既往肺动脉高压7%,心房扩张3%。40%的右心功能不全患者同时出现左心功能不全。讨论:心脏移植患者随访期间三尖瓣反流发生率为12.8%。观察到的主要机制是右心室扩张和功能障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Mechanisms of tricuspid insufficiency in the follow-up of patients post orthotopic heart transplantation].

Introduction: Tricuspid regurgitation (TR) is the most frequent valvulopathy after cardiac transplantation, with an incidence ranging from 19% to 84%. Severity increases with follow-up. The objectives were to describe the mechanisms involved in the development of post-transplantation TR.

Materials and methods: Single-center, retrospective cohort study including patients who received orthotopic heart transplantation between 2012 and 2022. Echocardiograms were performed at 6, 12 and 18 months' post-transplantation. The mechanisms of tricuspid regurgitation described were atrial dilatation or bi-atrial technique, multiple endomyocardial biopsies, right ventricular dilatation and dysfunction, previous pulmonary hypertension and mismatch of the recipient cavity with the transplanted organ.

Results: A total of 234 patients were included. The incidence of significant tricuspid regurgitation from 6 months post-transplantation was 12.8%. Right ventricular dilatation and dysfunction was the most prevalent mechanism in 67%, mismatch 17%, organic valve lesion and previous pulmonary hypertension 7% and atrial dilatation 3%. The 40% of patients who had right ventricular dysfunction also presented left ventricular dysfunction.

Discussion: The incidence of tricuspid regurgitation in heart transplant patients was 12.8% during the follow-up. The main mechanism observed was the right ventricular dilatation and dysfunction.

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来源期刊
Medicina-buenos Aires
Medicina-buenos Aires 医学-医学:内科
CiteScore
1.30
自引率
12.50%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Information not localized
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