NK/ t细胞骨淋巴瘤诱导的噬血细胞淋巴组织细胞增多症1例临床报告

Q4 Medicine

Radiology Case Reports Pub Date : 2025-04-08 DOI:10.1016/j.radcr.2025.03.025

Zhanrong Zhang MM, Feng Chen MD

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引用次数: 0

摘要

噬血细胞性淋巴组织细胞增多症（HLH）是一种严重的疾病，其特征是分泌大量的炎性细胞因子。淋巴瘤是继发性HLH的主要病因。本报告描述了一个最初诊断为HLH的儿童在治疗后复发的病例。初步诊断十个月后，在右上肢发现肿块，病理结果证实为NK/ t细胞淋巴瘤。根据患者的病史，这种淋巴瘤被认为是HLH的根本原因。诊断为淋巴瘤合并HLH的患者与未诊断为HLH的患者相比预后更差，生存期更短。早期诊断和及时对症治疗可显著改善患者预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report

Hemophagocytic lymphohistiocytosis (HLH) is a severe condition characterized by the secretion of large amounts of inflammatory cytokines. Lymphoma is a major cause of secondary HLH. This report describes the case of a child initially diagnosed with HLH who experienced recurrent episodes after treatment. Ten months after the initial diagnosis, a mass was discovered in the right upper limb, and pathology findings confirmed NK/T-cell lymphoma. Based on the patient's medical history, this lymphoma was considered the underlying cause of HLH. Patients diagnosed with lymphoma complicated by HLH have a worse prognosis and shorter survival compared with those without HLH. Early diagnosis and timely symptomatic treatment can significantly improve patient prognosis.

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来源期刊

Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

1.10

自引率

0.00%

发文量

1074

审稿时长

30 days

期刊介绍： The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.