幼年特发性关节炎关节的角度评估。

Rheumatology and immunology research Pub Date : 2025-04-02 eCollection Date: 2025-03-01 DOI:10.1515/rir-2025-0001
Sudip Banerjee, Atanu Adak, Debadyuti Dutta, Partha Pratim Pan, Manab Nandy, Avijit Hazra, Rakesh K Mondal
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引用次数: 0

摘要

背景:幼年特发性关节炎(JIA)中的关节畸形在儿童中最为常见,但并不以角度测量来定义。本研究旨在评估 JIA 患者受影响关节角度偏差的关节畸形情况:这项横断面研究在西孟加拉邦北孟加拉医学院小儿风湿病诊所进行。研究对象包括根据国际风湿病学协会联盟(ILAR)标准确诊为 JIA 的 2-16 岁儿童。患有并发症、血流动力学不稳定和其他急性病的患者被排除在外。使用角度计进行角度测量:患儿的平均年龄为(8.05 ± 3.20)岁,其中57.5%为男性。JIA的流行亚型为少关节型JIA(40%),其次是多关节型JIA(35%)和全身型JIA(12.5%)。常见的受累关节是膝关节(40%),其次是手部小关节(32.5%)、踝关节(30%)、腕关节和足关节(各占 17.5%)、肘关节(12.5%)和颈椎关节(7.5%)。在 pJIA 中,病程长短与受影响关节的数量显著相关(P = 0.017)。在少关节炎、多关节炎和严重关节炎中,观察到的主要是腕关节、膝关节和踝关节畸形。少关节炎患者的左右膝关节角度偏差(平均值±标度)分别为(2°±4.16°)和(1.87°±5.12°),pJIA患者的左右膝关节角度偏差分别为(13.36°±17.03°)和(12.5°±15.08°),sJIA患者的左右膝关节角度偏差分别为(3°±6.71°)和(2.4°±5.37°)。少JIA、pJIA和sJIA的右踝关节角度偏差分别为(2.62° ± 5.06)、(5.43° ± 8.21°)和(4° ± 8.94°)。少关节炎患者左右手腕的角度偏差分别为(1.25°±3.41°)和(0.94°±3.75°),pJIA患者为(4.07°±8.93°)和(4.14°±9.36°),sJIA患者为(2.45°±5.37°)和(2°±4.47°):本研究是印度第一项量化 JIA 变形关节角度偏差的研究。角度偏差可作为监测不同亚型 JIA 疾病进展的重要参数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Angular assessment of joints in juvenile idiopathic arthritis.

Background: Joint deformities in juvenile idiopathic arthritis (JIA) are most common in children, are not defined in term of angular measurements. The study was aimed to evaluate the joint deformities in angular deviation of the afected joints in JIA patients.

Methods: This cross-sectional study was conducted at Pediatric Rheumatology Clinic, North Bengal Medical College, West Bengal. The children aged 2-16 years diagnosed with JIA according to the International League of Associations for Rheumatology (ILAR) criteria were included in the study. Patients with co-morbid disease, hemodynamic instability, and other acute conditions were excluded. Angular measurements were performed using goniometer.

Results: The mean age of children was (8.05 ± 3.20) years of which 57.5% was male and the disease duration associated with the deformities in JIA. The prevalent subtypes of JIA were Oligoarticular JIA (oligoJIA)(40%), followed by polyarticular JIA (pJIA) (35%) and systemic-onset JIA (sJIA) (12.5%). The commonly involved joint were knee (40%), followed by small joint of hand (32.5%), ankle (30%), wrist and foot (17.5% each), elbow (12.5%) and cervical joint (7.5%). In pJIA, duration of disease significantly (P = 0.017) associated with the number of affected joints. Mostly, wrist, knee and ankle deformities were observed in oligoJIA, pJIA and sJIA. The angular deviation (mean ± SD) of right and left knee were (2° ± 4.16°) and (1.87° ± 5.12°) in oligoJIA, (13.36° ± 17.03°) and (12.5° ± 15.08°) in pJIA and (3° ± 6.71°) and (2.4° ± 5.37°) in sJIA. Right ankle angular deviation were (2.62° ± 5.06), (5.43° ± 8.21°) and 4° ± 8.94° respectively in oligoJIA, pJIA and sJIA. The angular deviation of right and left wrist were (1.25° ± 3.41°) and (0.94° ± 3.75°) in oligoJIA, (4.07° ± 8.93°) and (4.14° ± 9.36°) in pJIA and (2.45° ± 5.37°) and (2° ± 4.47°) in sJIA.

Conclusion: This study is the first study from India to quantify the angular deviation of deformed joints in JIA. Angular deviation could serve as a valuable parameter for monitoring disease progression across various JIA subtypes.

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