2003-2018年美国成年人使用加巴喷丁类药物的趋势。

IF 1.7 4区医学 Q3 CLINICAL NEUROLOGY

Neurological Research Pub Date : 2025-04-07 DOI:10.1080/01616412.2025.2490091

Hok Leong Chin

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引用次数: 0

摘要

本研究旨在调查加巴喷丁类药物在美国人群中的使用情况和趋势。它还旨在通过提供不同社会人口亚群体的额外背景，为当前文献做出贡献。方法：本研究利用2003-2004年周期至2017-2018年周期的数据，共包括115,554名20岁及以上的参与者。加巴喷丁类的使用是通过一份调查问卷来确定的，该问卷询问了过去30天内的处方药使用情况。采用STATA/SE 17.0进行加权分析。使用逻辑回归评估趋势。结果：加巴喷丁类药物的使用从2003-2004年的0.6% （95% CI, 0.4%-0.7%）显著增加到2017-2018年的1.8% (95% CI, 1.6%-2.0%)，主要是由于加巴喷丁使用率的增加。不同亚组的趋势相似。结论：研究结果显示，加巴喷丁类药物的使用大幅增加，特别是加巴喷丁，与其他研究一致。强调了安全问题，强调了滥用和误用的可能性，特别是在类阿片流行的情况下。

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Trends in use of gabapentinoids among adults in the United States from 2003-2018.

Introduction: This study aimed to investigate the prevalence and trends in gabapentinoid use among the US population. It also aimed to contribute to the current literature by providing additional context across different sociodemographic subgroups.

Methods: This study utilized data from the 2003-2004 cycles to the 2017-2018 cycles, including a total of 115,554 participants aged 20 years and older. Gabapentinoid use was determined through a questionnaire that inquired about prescription medication use during the past 30 days. Analyses were weighted and conducted using STATA/SE version 17.0. Trends were assessed using logistic regression.

Results: Gabapentinoid use significantly increased from 0.6% (95% CI, 0.4%-0.7%) in 2003-2004 to 1.8% (95% CI, 1.6%-2.0%) in 2017-2018, primarily driven by increased gabapentin utilization. The trends were similar across different subgroups.

Conclusions: The findings revealed a substantial rise in gabapentinoid use, particularly gabapentin, aligned with other studies. Safety concerns are underscored, emphasizing the potential for abuse and misuse, especially amid the opioid epidemic.

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来源期刊

Neurological Research 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

116

审稿时长

5.3 months

期刊介绍： Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields. The scope of the journal includes: •Stem cell applications •Molecular neuroscience •Neuropharmacology •Neuroradiology •Neurochemistry •Biomathematical models •Endovascular neurosurgery •Innovation in neurosurgery.