水-乙酸乙酯体系高效合成4-芳基喹啉的研究。

IF 2.5 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ChemistryOpen Pub Date : 2025-04-07 DOI:10.1002/open.202400470

Mohammad Qandalee, Aliyeh Khajeh-Khezri, Mohammad Alikarami, Silvia Izquierdo, Ignacio M López-Coca

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引用次数: 0

摘要

杂环化合物，尤其是芳基喹啉类化合物，因其多样化的生物和物理化学特性，在制药、材料科学和农用化学品领域具有极其重要的作用。然而，传统的合成方法通常依赖有机溶剂和催化剂，这不仅会引发环境和健康问题，而且需要高能量投入。为了应对这些挑战，本研究运用绿色化学原理，开发了一种可持续、高效和环保的芳基喹啉合成路线。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Exploring a Water-Ethyl Acetate System for the Efficient Synthesis of 4-Aryl Quinolines.

Heterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely on organic solvents and catalysts, which raise environmental and health concerns while requiring high energy inputs. This study addresses these challenges by applying the principles of green chemistry to develop a sustainable, efficient, and environmentally friendly synthetic route for aryl quinolines.

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来源期刊

ChemistryOpen CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

4.80

自引率

4.30%

发文量

143

审稿时长

1 months

期刊介绍： ChemistryOpen is a multidisciplinary, gold-road open-access, international forum for the publication of outstanding Reviews, Full Papers, and Communications from all areas of chemistry and related fields. It is co-owned by 16 continental European Chemical Societies, who have banded together in the alliance called ChemPubSoc Europe for the purpose of publishing high-quality journals in the field of chemistry and its border disciplines. As some of the governments of the countries represented in ChemPubSoc Europe have strongly recommended that the research conducted with their funding is freely accessible for all readers (Open Access), ChemPubSoc Europe was concerned that no journal for which the ethical standards were monitored by a chemical society was available for such papers. ChemistryOpen fills this gap.