治疗挑战在管理的VEXAS综合征：一个病例报告。

IF 2.2 4区医学 Q2 DERMATOLOGY

Australasian Journal of Dermatology Pub Date : 2025-04-06 DOI:10.1111/ajd.14478

Georgia Kelly, Yolanka Lobo, Amanda Godbolt

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引用次数: 0

摘要

VEXAS综合征是一种新发现的自身炎症和血液学疾病，具有不同的皮肤和全身表现。我们提出一个病例的VEXAS综合征在一个63岁的男性治疗顽固性坏疽性脓皮病和复杂的皮肤和系统的历史。我们希望它能告知并鼓励皮肤科医生考虑对任何50岁以上的男性中性粒细胞皮肤病和不明原因的自身炎症的VEXAS综合征进行早期诊断测试。

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Therapeutic Challenges in the Management of VEXAS Syndrome: A Case Report.

VEXAS syndrome is a newly described autoinflammatory and haematologic condition that has variable cutaneous and systemic presentations. We present a case of VEXAS syndrome in a 63-year-old male with treatment refractory pyoderma gangrenosum and a complex dermatologic and systemic history. We hope it informs and encourages dermatologists to consider early diagnostic testing for VEXAS syndrome in any male over 50 years of age with a neutrophilic dermatosis and unexplained autoinflammation.

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来源期刊

Australasian Journal of Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

5.00%

发文量

186

审稿时长

6-12 weeks

期刊介绍： Australasian Journal of Dermatology is the official journal of the Australasian College of Dermatologists and the New Zealand Dermatological Society, publishing peer-reviewed, original research articles, reviews and case reports dealing with all aspects of clinical practice and research in dermatology. Clinical presentations, medical and physical therapies and investigations, including dermatopathology and mycology, are covered. Short articles may be published under the headings ‘Signs, Syndromes and Diagnoses’, ‘Dermatopathology Presentation’, ‘Vignettes in Contact Dermatology’, ‘Surgery Corner’ or ‘Letters to the Editor’.