Ramazan Astan, Fehmi Kacmaz, Ersin Saricam, Erdogan Ilkay
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We evaluated P-wave parameters in terms of defect size, duration of the volume overload, and closure device sizes.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Pmax and PWD were significantly decreased after the procedure compared with the values before the procedure (<i>p</i> < 0.001). Pmax values had a statistically significant correlation with ASD size (< 20 mm or ≥ 20 mm) both before and after the procedure. Pmax values were significantly higher in patients older than 30 years of age (119.6 ± 19.5 vs. 102.7 ± 17.1 ms, respectively; <i>p</i> = 0.039). A significantly positive correlation was found between pre- and post-procedural Pmax and defect sizes (<i>r</i> = 0.474, <i>p</i> = 0.019 and <i>r</i> = 0.4233, <i>p</i> = 0.04, respectively). However, no positive correlation between PWD and defect age and size was present.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Percutaneous closure of ASD is associated with an immediate decrease in both Pd and Pmax that seems to be related to the acute volume overload cessation in cardiac chambers.</p>\n </section>\n </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"30 3","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.70076","citationCount":"0","resultStr":"{\"title\":\"The Evaluation of P-Wave Parameters in Patients With Percutaneous Closure of Atrial Septal Defect\",\"authors\":\"Ramazan Astan, Fehmi Kacmaz, Ersin Saricam, Erdogan Ilkay\",\"doi\":\"10.1111/anec.70076\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Atrial septal defect (ASD) can lead to volume overload and related changes in P-wave parameters in surface electrocardiograms of these patients. In this study, we aimed to evaluate the effect of volume overload on P-wave parameters in patients with ASD.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Materials and Methods</h3>\\n \\n <p>This study is a retrospective cohort analysis. A total of 142 patients with secundum ASD who underwent percutaneous closure were evaluated. P-wave duration (Pmax) and P-wave dispersion (PWD) were measured on the surface ECG before and 1 h after the closure procedure. We evaluated P-wave parameters in terms of defect size, duration of the volume overload, and closure device sizes.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Pmax and PWD were significantly decreased after the procedure compared with the values before the procedure (<i>p</i> < 0.001). Pmax values had a statistically significant correlation with ASD size (< 20 mm or ≥ 20 mm) both before and after the procedure. 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引用次数: 0
摘要
背景房间隔缺损（房间隔缺损，ASD）可导致房间隔缺损患者体表心电图容量过载及相关p波参数改变。在这项研究中，我们旨在评估容量过载对ASD患者p波参数的影响。材料与方法本研究采用回顾性队列分析。对142例经皮缝合的继发性ASD患者进行了评估。在闭合前和闭合后1 h测量体表心电图p波持续时间（Pmax）和p波弥散度（PWD）。我们根据缺陷大小、体积过载持续时间和闭合装置大小来评估p波参数。结果术后Pmax和PWD较术前显著降低（p < 0.001）。术前和术后Pmax值与ASD大小（≤20 mm或≥20 mm）均有统计学意义。30岁以上患者的Pmax值明显更高（分别为119.6±19.5 ms和102.7±17.1 ms）；p = 0.039)。术前和术后Pmax与缺陷大小呈显著正相关（r = 0.474, p = 0.019和r = 0.4233, p = 0.04）。然而，PWD与缺陷年龄和尺寸没有正相关。结论经皮ASD闭合与Pd和Pmax的立即下降有关，这似乎与心室容量过载的急性停止有关。
The Evaluation of P-Wave Parameters in Patients With Percutaneous Closure of Atrial Septal Defect
Background
Atrial septal defect (ASD) can lead to volume overload and related changes in P-wave parameters in surface electrocardiograms of these patients. In this study, we aimed to evaluate the effect of volume overload on P-wave parameters in patients with ASD.
Materials and Methods
This study is a retrospective cohort analysis. A total of 142 patients with secundum ASD who underwent percutaneous closure were evaluated. P-wave duration (Pmax) and P-wave dispersion (PWD) were measured on the surface ECG before and 1 h after the closure procedure. We evaluated P-wave parameters in terms of defect size, duration of the volume overload, and closure device sizes.
Results
Pmax and PWD were significantly decreased after the procedure compared with the values before the procedure (p < 0.001). Pmax values had a statistically significant correlation with ASD size (< 20 mm or ≥ 20 mm) both before and after the procedure. Pmax values were significantly higher in patients older than 30 years of age (119.6 ± 19.5 vs. 102.7 ± 17.1 ms, respectively; p = 0.039). A significantly positive correlation was found between pre- and post-procedural Pmax and defect sizes (r = 0.474, p = 0.019 and r = 0.4233, p = 0.04, respectively). However, no positive correlation between PWD and defect age and size was present.
Conclusion
Percutaneous closure of ASD is associated with an immediate decrease in both Pd and Pmax that seems to be related to the acute volume overload cessation in cardiac chambers.
期刊介绍：
The ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (A.N.E) is an online only journal that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients.
ANE is the first journal in an evolving subspecialty that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. The publication includes topics related to 12-lead, exercise and high-resolution electrocardiography, arrhythmias, ischemia, repolarization phenomena, heart rate variability, circadian rhythms, bioengineering technology, signal-averaged ECGs, T-wave alternans and automatic external defibrillation.
ANE publishes peer-reviewed articles of interest to clinicians and researchers in the field of noninvasive electrocardiology. Original research, clinical studies, state-of-the-art reviews, case reports, technical notes, and letters to the editors will be published to meet future demands in this field.
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