{"title":"头颈部肿瘤与神经内分泌标志物“表达”:陷阱和学习点","authors":"Ella-Grace Kirton, Karwan Moutasim","doi":"10.1016/j.mpdhp.2025.02.004","DOIUrl":null,"url":null,"abstract":"<div><div>Poorly differentiated carcinomas can be a challenging area for histopathologists and frequently require ancillary tests to arrive at a definitive diagnosis. Neuroendocrine markers have the potential to be helpful in establishing a diagnosis but can also cause diagnostic dilemmas when aberrantly expressed. Here, we present three case examples to illustrate this issue and highlight relevant learning points in each case.</div></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"31 4","pages":"Pages 221-227"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Head and neck tumours with neuroendocrine marker ‘expression’: pitfalls and learning points\",\"authors\":\"Ella-Grace Kirton, Karwan Moutasim\",\"doi\":\"10.1016/j.mpdhp.2025.02.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Poorly differentiated carcinomas can be a challenging area for histopathologists and frequently require ancillary tests to arrive at a definitive diagnosis. Neuroendocrine markers have the potential to be helpful in establishing a diagnosis but can also cause diagnostic dilemmas when aberrantly expressed. Here, we present three case examples to illustrate this issue and highlight relevant learning points in each case.</div></div>\",\"PeriodicalId\":39961,\"journal\":{\"name\":\"Diagnostic Histopathology\",\"volume\":\"31 4\",\"pages\":\"Pages 221-227\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic Histopathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1756231725000143\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231725000143","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Head and neck tumours with neuroendocrine marker ‘expression’: pitfalls and learning points
Poorly differentiated carcinomas can be a challenging area for histopathologists and frequently require ancillary tests to arrive at a definitive diagnosis. Neuroendocrine markers have the potential to be helpful in establishing a diagnosis but can also cause diagnostic dilemmas when aberrantly expressed. Here, we present three case examples to illustrate this issue and highlight relevant learning points in each case.
期刊介绍:
This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.