Xiye Zhou , Vasyl Skorych , Katja Milkreiter , Ricarda Leister , Stefan Heinrich
{"title":"用动态流程模拟优化工业连续流化床干燥机乳糖干燥过程的效率","authors":"Xiye Zhou , Vasyl Skorych , Katja Milkreiter , Ricarda Leister , Stefan Heinrich","doi":"10.1016/j.apt.2025.104864","DOIUrl":null,"url":null,"abstract":"<div><div>The fluidized bed drying of wet lactose plays a crucial role in the industrial production of lactose powder for pharmaceutical purposes. Currently, such a process is often controlled using empirical operating parameters, which may result in variability in product properties and suboptimal consumption of resources and energy. Hence, the work presented in our paper aims to address this issue by proposing a new dynamic fluidized bed dryer model for wet lactose drying in the flowsheet simulation framework Dyssol. This model was implemented based on fundamental equations for heat and mass balance, thermodynamics, and powder drying kinetics. It enables a fast and accurate prediction of the product moisture content and the exhaust air temperature for a wide range of wet lactose flow rates, fluidization air flow rates, and fluidization air temperatures. Optimization was conducted based on the proposed model, offering a pathway to reduce energy consumption and stabilize product properties. Furthermore, this model contributes to establishing a digital twin, which provides real-time simulation and optimization of the entire lactose production process beyond conventional flowsheet modelling. Incorporating further process units for the upstream and downstream treatments will allow for faster and more efficient control of existing processes and facilitate the implementation of more advanced optimization techniques.</div></div>","PeriodicalId":7232,"journal":{"name":"Advanced Powder Technology","volume":"36 6","pages":"Article 104864"},"PeriodicalIF":4.2000,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Optimization of efficiency of lactose drying process in an industrial continuous fluidized bed dryer using dynamic flowsheet simulation\",\"authors\":\"Xiye Zhou , Vasyl Skorych , Katja Milkreiter , Ricarda Leister , Stefan Heinrich\",\"doi\":\"10.1016/j.apt.2025.104864\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The fluidized bed drying of wet lactose plays a crucial role in the industrial production of lactose powder for pharmaceutical purposes. Currently, such a process is often controlled using empirical operating parameters, which may result in variability in product properties and suboptimal consumption of resources and energy. Hence, the work presented in our paper aims to address this issue by proposing a new dynamic fluidized bed dryer model for wet lactose drying in the flowsheet simulation framework Dyssol. This model was implemented based on fundamental equations for heat and mass balance, thermodynamics, and powder drying kinetics. It enables a fast and accurate prediction of the product moisture content and the exhaust air temperature for a wide range of wet lactose flow rates, fluidization air flow rates, and fluidization air temperatures. Optimization was conducted based on the proposed model, offering a pathway to reduce energy consumption and stabilize product properties. Furthermore, this model contributes to establishing a digital twin, which provides real-time simulation and optimization of the entire lactose production process beyond conventional flowsheet modelling. Incorporating further process units for the upstream and downstream treatments will allow for faster and more efficient control of existing processes and facilitate the implementation of more advanced optimization techniques.</div></div>\",\"PeriodicalId\":7232,\"journal\":{\"name\":\"Advanced Powder Technology\",\"volume\":\"36 6\",\"pages\":\"Article 104864\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2025-04-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Powder Technology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0921883125000858\",\"RegionNum\":2,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, CHEMICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Powder Technology","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0921883125000858","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, CHEMICAL","Score":null,"Total":0}
Optimization of efficiency of lactose drying process in an industrial continuous fluidized bed dryer using dynamic flowsheet simulation
The fluidized bed drying of wet lactose plays a crucial role in the industrial production of lactose powder for pharmaceutical purposes. Currently, such a process is often controlled using empirical operating parameters, which may result in variability in product properties and suboptimal consumption of resources and energy. Hence, the work presented in our paper aims to address this issue by proposing a new dynamic fluidized bed dryer model for wet lactose drying in the flowsheet simulation framework Dyssol. This model was implemented based on fundamental equations for heat and mass balance, thermodynamics, and powder drying kinetics. It enables a fast and accurate prediction of the product moisture content and the exhaust air temperature for a wide range of wet lactose flow rates, fluidization air flow rates, and fluidization air temperatures. Optimization was conducted based on the proposed model, offering a pathway to reduce energy consumption and stabilize product properties. Furthermore, this model contributes to establishing a digital twin, which provides real-time simulation and optimization of the entire lactose production process beyond conventional flowsheet modelling. Incorporating further process units for the upstream and downstream treatments will allow for faster and more efficient control of existing processes and facilitate the implementation of more advanced optimization techniques.
期刊介绍:
The aim of Advanced Powder Technology is to meet the demand for an international journal that integrates all aspects of science and technology research on powder and particulate materials. The journal fulfills this purpose by publishing original research papers, rapid communications, reviews, and translated articles by prominent researchers worldwide.
The editorial work of Advanced Powder Technology, which was founded as the International Journal of the Society of Powder Technology, Japan, is now shared by distinguished board members, who operate in a unique framework designed to respond to the increasing global demand for articles on not only powder and particles, but also on various materials produced from them.
Advanced Powder Technology covers various areas, but a discussion of powder and particles is required in articles. Topics include: Production of powder and particulate materials in gases and liquids(nanoparticles, fine ceramics, pharmaceuticals, novel functional materials, etc.); Aerosol and colloidal processing; Powder and particle characterization; Dynamics and phenomena; Calculation and simulation (CFD, DEM, Monte Carlo method, population balance, etc.); Measurement and control of powder processes; Particle modification; Comminution; Powder handling and operations (storage, transport, granulation, separation, fluidization, etc.)