Nieves Larrosa , Montserrat Giménez , Mónica Ballestero-Téllez , Sergi Hernández , Alexander Almendral , Juan P. Horcajada , Susana Melendo , M Pilar García , Albert Boada , Enric Limón , Miquel Pujol , on behalf of the microbiologists of the participating laboratories in VINCat-PROA
{"title":"加泰罗尼亚成人和儿科人群抗菌药物敏感性的综合监测：来自社区、医院和长期护理机构设置的见解","authors":"Nieves Larrosa , Montserrat Giménez , Mónica Ballestero-Téllez , Sergi Hernández , Alexander Almendral , Juan P. Horcajada , Susana Melendo , M Pilar García , Albert Boada , Enric Limón , Miquel Pujol , on behalf of the microbiologists of the participating laboratories in VINCat-PROA","doi":"10.1016/j.eimce.2024.12.012","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>This study presents comprehensive data on antimicrobial susceptibility across healthcare settings and age groups in Catalonia, Spain.</div></div><div><h3>Methods</h3><div>Susceptibility data were collected from 37 microbiology laboratories between 2020 and 2022 for community-acquired infections (CAIs), and 2021 and 2022 for hospital and long-term care facilities (LTCFs). Susceptibility was calculated based on the proportion of susceptible strains among the total strains.</div></div><div><h3>Results</h3><div>Pediatrics: Community-acquired infections (CAIs): in urinary tract infections (UTIs), extended-spectrum beta-lactamase production (ESBL-P) <em>Escherichia coli</em> was 3.8%. <em>Streptococcus pneumoniae</em> was highly susceptible to penicillins (97.5%). Community-acquired methicillin-resistant <em>Staphylococcus aureus</em> was 6.8%. Hospital-acquired infections (HAIs): ESBL-P in <em>E. coli</em> and <em>Klebsiella pneumoniae</em> were 6.7% and 9.4%. Carbapenem resistance in <em>Enterobacter cloacae</em> complex was less than 1%. Extremely drug-resistant <em>Pseudomonas aeruginosa</em> was 1.6%.</div></div><div><h3>Adults</h3><div>CAIs: In UTIs, <em>E. coli</em> showed high susceptibility to fosfomycin (>95%) and 9% of ESBL-P. In respiratory tract infections, <em>Streptococcus pyogenes</em> exhibited reduced susceptibility to macrolides (67%) and clindamycin (75.1%), while <em>Haemophilus influenzae</em> and <em>S. pneumoniae</em> remained susceptible to penicillins (78% and 96%). HAIs: <em>E. coli</em> showed 12.8% of ESBL-P and <em>K. pneumoniae</em> 20%. Carbapenem resistance was mainly identified in <em>E. cloacae</em> (2.8%) and <em>K. pneumoniae</em> (2.2%). <em>P. aeruginosa</em> showed high susceptibility to meropenem (87%). Methicillin-resistance was detected in 22% of <em>S. aureus</em>.</div><div>Long-term care facilities (LTCFs): <em>E. coli</em> causing UTI was highly susceptible to carbapenems (99%), nitrofurantoin (96%), and fosfomycin (93%) with 25.8% of ESBL-P. <em>K. pneumoniae</em> showed 40% ESBL-P and 2.9% of carbapenem resistance. <em>P. aeruginosa</em> exhibited decreased susceptibility to quinolones (69.5%) and highly susceptibility to meropenem (88.5%).</div></div><div><h3>Conclusion</h3><div>The data underscore the necessity of stratified susceptibility reports by setting, type of infection, and age.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 ","pages":"Pages S80-S89"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comprehensive surveillance of antimicrobial susceptibility across adult and pediatric populations in Catalonia: Insights from community, hospital, and long-term care facility settings\",\"authors\":\"Nieves Larrosa , Montserrat Giménez , Mónica Ballestero-Téllez , Sergi Hernández , Alexander Almendral , Juan P. Horcajada , Susana Melendo , M Pilar García , Albert Boada , Enric Limón , Miquel Pujol , on behalf of the microbiologists of the participating laboratories in VINCat-PROA\",\"doi\":\"10.1016/j.eimce.2024.12.012\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>This study presents comprehensive data on antimicrobial susceptibility across healthcare settings and age groups in Catalonia, Spain.</div></div><div><h3>Methods</h3><div>Susceptibility data were collected from 37 microbiology laboratories between 2020 and 2022 for community-acquired infections (CAIs), and 2021 and 2022 for hospital and long-term care facilities (LTCFs). Susceptibility was calculated based on the proportion of susceptible strains among the total strains.</div></div><div><h3>Results</h3><div>Pediatrics: Community-acquired infections (CAIs): in urinary tract infections (UTIs), extended-spectrum beta-lactamase production (ESBL-P) <em>Escherichia coli</em> was 3.8%. <em>Streptococcus pneumoniae</em> was highly susceptible to penicillins (97.5%). Community-acquired methicillin-resistant <em>Staphylococcus aureus</em> was 6.8%. Hospital-acquired infections (HAIs): ESBL-P in <em>E. coli</em> and <em>Klebsiella pneumoniae</em> were 6.7% and 9.4%. Carbapenem resistance in <em>Enterobacter cloacae</em> complex was less than 1%. Extremely drug-resistant <em>Pseudomonas aeruginosa</em> was 1.6%.</div></div><div><h3>Adults</h3><div>CAIs: In UTIs, <em>E. coli</em> showed high susceptibility to fosfomycin (>95%) and 9% of ESBL-P. In respiratory tract infections, <em>Streptococcus pyogenes</em> exhibited reduced susceptibility to macrolides (67%) and clindamycin (75.1%), while <em>Haemophilus influenzae</em> and <em>S. pneumoniae</em> remained susceptible to penicillins (78% and 96%). HAIs: <em>E. coli</em> showed 12.8% of ESBL-P and <em>K. pneumoniae</em> 20%. Carbapenem resistance was mainly identified in <em>E. cloacae</em> (2.8%) and <em>K. pneumoniae</em> (2.2%). <em>P. aeruginosa</em> showed high susceptibility to meropenem (87%). Methicillin-resistance was detected in 22% of <em>S. aureus</em>.</div><div>Long-term care facilities (LTCFs): <em>E. coli</em> causing UTI was highly susceptible to carbapenems (99%), nitrofurantoin (96%), and fosfomycin (93%) with 25.8% of ESBL-P. <em>K. pneumoniae</em> showed 40% ESBL-P and 2.9% of carbapenem resistance. <em>P. aeruginosa</em> exhibited decreased susceptibility to quinolones (69.5%) and highly susceptibility to meropenem (88.5%).</div></div><div><h3>Conclusion</h3><div>The data underscore the necessity of stratified susceptibility reports by setting, type of infection, and age.</div></div>\",\"PeriodicalId\":72916,\"journal\":{\"name\":\"Enfermedades infecciosas y microbiologia clinica (English ed.)\",\"volume\":\"43 \",\"pages\":\"Pages S80-S89\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Enfermedades infecciosas y microbiologia clinica (English ed.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2529993X25000620\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Enfermedades infecciosas y microbiologia clinica (English ed.)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2529993X25000620","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comprehensive surveillance of antimicrobial susceptibility across adult and pediatric populations in Catalonia: Insights from community, hospital, and long-term care facility settings
Background
This study presents comprehensive data on antimicrobial susceptibility across healthcare settings and age groups in Catalonia, Spain.
Methods
Susceptibility data were collected from 37 microbiology laboratories between 2020 and 2022 for community-acquired infections (CAIs), and 2021 and 2022 for hospital and long-term care facilities (LTCFs). Susceptibility was calculated based on the proportion of susceptible strains among the total strains.
Results
Pediatrics: Community-acquired infections (CAIs): in urinary tract infections (UTIs), extended-spectrum beta-lactamase production (ESBL-P) Escherichia coli was 3.8%. Streptococcus pneumoniae was highly susceptible to penicillins (97.5%). Community-acquired methicillin-resistant Staphylococcus aureus was 6.8%. Hospital-acquired infections (HAIs): ESBL-P in E. coli and Klebsiella pneumoniae were 6.7% and 9.4%. Carbapenem resistance in Enterobacter cloacae complex was less than 1%. Extremely drug-resistant Pseudomonas aeruginosa was 1.6%.
Adults
CAIs: In UTIs, E. coli showed high susceptibility to fosfomycin (>95%) and 9% of ESBL-P. In respiratory tract infections, Streptococcus pyogenes exhibited reduced susceptibility to macrolides (67%) and clindamycin (75.1%), while Haemophilus influenzae and S. pneumoniae remained susceptible to penicillins (78% and 96%). HAIs: E. coli showed 12.8% of ESBL-P and K. pneumoniae 20%. Carbapenem resistance was mainly identified in E. cloacae (2.8%) and K. pneumoniae (2.2%). P. aeruginosa showed high susceptibility to meropenem (87%). Methicillin-resistance was detected in 22% of S. aureus.
Long-term care facilities (LTCFs): E. coli causing UTI was highly susceptible to carbapenems (99%), nitrofurantoin (96%), and fosfomycin (93%) with 25.8% of ESBL-P. K. pneumoniae showed 40% ESBL-P and 2.9% of carbapenem resistance. P. aeruginosa exhibited decreased susceptibility to quinolones (69.5%) and highly susceptibility to meropenem (88.5%).
Conclusion
The data underscore the necessity of stratified susceptibility reports by setting, type of infection, and age.
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