Multisystem Inflammatory Syndrome in Children: A Case Report on Increased Intracranial Pressure.

This case study examines the uncommon complication of increased intracranial pressure (ICP) in refractory multisystem inflammatory syndrome in children (MIS-C). Due to the rare condition, there are few cases and randomized control trials that report on the association with increased ICP. This case report discusses the importance of monitoring for symptoms of increased ICP and adverse effects of cyclosporine A, as this agent has been used in some cases of refractory MIS-C. Ultimately the patient in this case study experienced no significant long-term complications. Current clinical recommendations include intravenous immunoglobulins and corticosteroids as the first-line therapy and adding biologic therapies for refractory cases. Patients should be screened for obesity, as it is a risk factor for intracranial hypertension. Lastly, invasive ICP monitoring can be used for severe cases of intracranial hypertension.