基于主观垂直冲突理论的个体晕动病症状进展计算模型构建。

IF 1.7 4区 医学 Q4 NEUROSCIENCES
Shota Inoue, Van Trong Dang, Hailong Liu, Takahiro Wada
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引用次数: 0

摘要

预测晕动病的计算模型已经取得了进展,特别是那些基于主观垂直冲突(SVC)理论的模型。虽然基于svc的模型主要预测晕动病发生率(MSI),即在给定动作下会呕吐的人的百分比,但仍然需要预测轻微个体症状的模型,这对日常应用至关重要。最近,通过将6DOF-SVC模型的输出从MSI更改为痛苦量表(MISC),使用SVC理论开发了预测前庭运动病进展的计算模型,痛苦量表是症状进展的主观衡量标准。在实际应用中,预测未见运动的MISC的能力是至关重要的。本研究设想了一种方法,通过从收集到该点的数据中识别参数来预测未来某一点以上的MISC。因此,本研究探讨用于参数识别的数据点数量对未来预测精度的影响。观察到的在黑暗中暴露于线性横向运动的参与者的MISC反应被用于模型验证。结果表明,随着数据点的增加,预测精度有所提高。平均而言,与使用参与者平均参数集的模型相比,使用超过5-10分钟的数据显着提高了准确性,尽管基于个人MISC历史的趋势显着不同。一项考虑个体MISC病史的试验,在观察到的MISC首次达到一定水平时定义数据点,显示当使用MISC 3级数据时准确性提高的总体趋势。本研究结果表明,结合个体症状病史可以有效地预测晕动病的症状进展,减少误差,从而为开发更广泛应用的个性化晕动病预测模型奠定了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Construction of a computational model of individual progression of motion sickness symptoms based on subjective vertical conflict theory.

Computational models predicting motion sickness have advanced, particularly those based on subjective vertical conflict (SVC) theory. While SVC-based models primarily predict motion sickness incidence (MSI), which is defined as the percentage of people who would vomit under a given motion, models predicting milder individual symptoms, which are crucial for daily applications, are still required. Recently, computational models predicting vestibular motion-sickness progression using the SVC theory have been developed by changing the output of a 6DOF-SVC model from MSI to the Misery Scale (MISC), a subjective measure of symptom progression. In practical applications, the ability to predict MISC for unseen motions is crucial. The present study conceived a method for predicting MISC beyond a certain point in the future by identifying parameters from data collected up to that point. Therefore, this study investigates the effect of the number of data points used for parameter identification on the future prediction accuracy. Observed MISC responses from participants exposed to linear lateral motion in darkness were used for model validation. The results indicated that prediction accuracy increased as more data points were included. On average, using more than 5-10 min of data significantly increased the accuracy compared to a model using averaged parameter sets across participants, although the tendency significantly differed based on an individual's MISC history. A trial considering individual MISC histories, in which data points were defined when the observed MISC first reached certain levels, showed a general trend of improved accuracy when data up to MISC Level 3 was used. The findings of this study demonstrate that motion sickness symptom progression can be predicted with reduced error by incorporating individual symptom histories, thereby providing a foundation for the development of personalized motion sickness prediction models applicable to broader applications.

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来源期刊
CiteScore
3.60
自引率
5.00%
发文量
228
审稿时长
1 months
期刊介绍: Founded in 1966, Experimental Brain Research publishes original contributions on many aspects of experimental research of the central and peripheral nervous system. The focus is on molecular, physiology, behavior, neurochemistry, developmental, cellular and molecular neurobiology, and experimental pathology relevant to general problems of cerebral function. The journal publishes original papers, reviews, and mini-reviews.
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