儿童青少年SARS-CoV-2感染的临床表现及转归

IF 6.1 3区医学 Q1 IMMUNOLOGY

Infectious disease clinics of North America Pub Date : 2025-04-04 DOI:10.1016/j.idc.2025.02.018

Andrew T Pavia

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引用次数: 0

摘要

与成年人相比，儿童更有可能出现无症状感染或类似于其他病毒感染的轻至中度SARS-CoV-2感染症状。然而，相当大比例的儿童患有严重疾病；2000多名美国儿童死于COVID-19，远远超过流感死亡人数。严重疾病的危险因素包括年龄小于6个月和12至17岁，以及存在基础疾病，特别是两种或两种以上的疾病。儿童多系统炎症综合征是一种危及生命的儿童感染后并发症。儿童会出现SARS-CoV-2急性后后遗症，但发生率低于成人。

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Clinical Manifestations and Outcomes of SARS-CoV-2 Infection in Children and Adolescents.

Compared to adults, children are more likely to experience asymptomatic infections or mild-to-moderate symptoms of SARS-CoV-2 infection that resemble other viral infections. However, a substantial proportion of children experience severe disease; more than 2000 US children have died of COVID-19, significantly exceeding the death toll from influenza. Risk factors for severe disease include age less than 6 months and 12 to 17 years, as well as the presence of underlying conditions, especially 2 or more conditions. Multisystem inflammatory syndrome in children is a life-threatening post-infectious complication seen in children. Children experience post-acute sequelae of SARS-CoV-2 but at lower rates than adults.

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来源期刊

Infectious disease clinics of North America 医学-传染病学

CiteScore

8.30

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Infectious Disease Clinics of North America updates you on the latest trends in the clinical diagnosis and management of patients with infectious diseases, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue focuses on a single topic in infectious disease, including clinical microbiology, compromised host infections, gastrointestinal infections, global health, hepatitis, HIV/AIDS, hospital-acquired infections, travel medicine, infection control, bacterial infections, sexually transmitted diseases, urinary tract infections, and viral infections.