治疗顺序的建模成本-效果分析

IF 5.4 2区经济学 Q1 ECONOMICS

Socio-economic Planning Sciences Pub Date : 2025-04-01 DOI:10.1016/j.seps.2025.102210

Cristina del Campo , Jiaru Bai , L. Robin Keller

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引用次数: 0

摘要

在临床实践中，癌症患者经常接受一系列药物的治疗，通常是因为随着时间的推移，药物的效果会逐渐减弱或产生耐药性。然而，很少有成本效益分析将这一事实纳入其模型。本文旨在通过提出一个模型来缩小这一差距，该模型反映了患者在其生命的长期持续时间内从一种治疗剂切换到另一种治疗剂的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Modeling cost-effectiveness analysis of treatment sequencing

In clinical practice, patients with cancer often undergo treatment with a sequence of drugs, usually because of diminishing effectiveness over time or resistance development. However, few cost-effectiveness analyses have included that fact in their model. This paper aims at closing that gap by presenting a model that reflects the possibility of the patient switching from one therapeutic agent to another one throughout the long-term duration of his/her life.

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来源期刊

Socio-economic Planning Sciences OPERATIONS RESEARCH & MANAGEMENT SCIENCE-

CiteScore

9.40

自引率

13.10%

发文量

294

审稿时长

58 days

期刊介绍： Studies directed toward the more effective utilization of existing resources, e.g. mathematical programming models of health care delivery systems with relevance to more effective program design; systems analysis of fire outbreaks and its relevance to the location of fire stations; statistical analysis of the efficiency of a developing country economy or industry. Studies relating to the interaction of various segments of society and technology, e.g. the effects of government health policies on the utilization and design of hospital facilities; the relationship between housing density and the demands on public transportation or other service facilities: patterns and implications of urban development and air or water pollution. Studies devoted to the anticipations of and response to future needs for social, health and other human services, e.g. the relationship between industrial growth and the development of educational resources in affected areas; investigation of future demands for material and child health resources in a developing country; design of effective recycling in an urban setting.