Anna O Subbotina, Vyacheslav V Martemyanov, Irina A Belousova
{"title":"dscpv1在大规模生产候选者中的不典型发病机制（鳞翅目：鞘科）。","authors":"Anna O Subbotina, Vyacheslav V Martemyanov, Irina A Belousova","doi":"10.1093/jee/toaf047","DOIUrl":null,"url":null,"abstract":"<p><p>Recently obtained cypovirus strain DsCPV-1 shows potential as a biological insecticide, with its alternative host Manduca sexta (L.) being a promising producer. We confirmed DsCPV-1 replication in M. sexta by quantitative PCR, validating DsCPV-1's suitability as a biological producer. At the terminal infection stage, we revealed many nonoccluded DsCPV-1 virions by transmission electron microscopy, indicating virus replication with reduced or without polyhedron formation in this alternative host.</p>","PeriodicalId":94077,"journal":{"name":"Journal of economic entomology","volume":" ","pages":"1436-1440"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Atypical pathogenesis of DsCPV-1 in candidate for mass production Manduca sexta (Lepidoptera: Sphingidae).\",\"authors\":\"Anna O Subbotina, Vyacheslav V Martemyanov, Irina A Belousova\",\"doi\":\"10.1093/jee/toaf047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Recently obtained cypovirus strain DsCPV-1 shows potential as a biological insecticide, with its alternative host Manduca sexta (L.) being a promising producer. We confirmed DsCPV-1 replication in M. sexta by quantitative PCR, validating DsCPV-1's suitability as a biological producer. At the terminal infection stage, we revealed many nonoccluded DsCPV-1 virions by transmission electron microscopy, indicating virus replication with reduced or without polyhedron formation in this alternative host.</p>\",\"PeriodicalId\":94077,\"journal\":{\"name\":\"Journal of economic entomology\",\"volume\":\" \",\"pages\":\"1436-1440\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of economic entomology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/jee/toaf047\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of economic entomology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/jee/toaf047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Atypical pathogenesis of DsCPV-1 in candidate for mass production Manduca sexta (Lepidoptera: Sphingidae).
Recently obtained cypovirus strain DsCPV-1 shows potential as a biological insecticide, with its alternative host Manduca sexta (L.) being a promising producer. We confirmed DsCPV-1 replication in M. sexta by quantitative PCR, validating DsCPV-1's suitability as a biological producer. At the terminal infection stage, we revealed many nonoccluded DsCPV-1 virions by transmission electron microscopy, indicating virus replication with reduced or without polyhedron formation in this alternative host.
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