{"title":"单纯性近视和复合性近视散光屈光不正成分与高阶像差的关系。","authors":"Sahar Mohaghegh, Shahram Bamdad, Haleh Kangari, Saeed Rahmani","doi":"10.3389/fopht.2025.1532931","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To investigate associations between refractive error components and higher-order aberrations (HOAs) in adult myopic subjects.</p><p><strong>Methods: </strong>A total of 1370 myopia right eyes, aged 18-40, were included in a cross-sectional study. Subjective cycloplegic refractions and distance aberrometry measured with a Shack-Hartmann device were analyzed. Zernike components of horizontal coma (Z<sub>3</sub> <sup>1</sup>), vertical coma (Z<sub>3</sub> <sup>-1</sup>), oblique trefoil (Z<sub>3</sub> <sup>3</sup>), vertical trefoil (Z<sub>3</sub> <sup>-3</sup>), spherical aberration, and total root-mean-square (RMS) wave-front error for 6 mm pupil were analyzed. Pearson's correlations were calculated between sphero-cylindrical components and HOAs based on vector analysis for the astigmatism axis. Total subjects were divided into two subgroups: simple myopia (SMY, 648 eyes) and compound myopic astigmatism (CMA, 722 eyes). HOAs were compared between the two subgroups.</p><p><strong>Results: </strong>Total RMS wave-front error correlates with spherical equivalent myopia (r = -0.1, P<0.05) and J45 (r = 0.1, P<0.001). J0 correlates positively with vertical coma (Z<sub>3</sub> <sup>-1</sup>) (r = 0.1 p <0.001) and negatively with oblique trefoil (Z<sub>3</sub> <sup>3</sup>) and vertical trefoil (Z<sub>3</sub> <sup>-3</sup>), (r = -0.1, p < 0.001; r = -0.1, P < 0.05). The total RMS wavefront-error was larger in the CMA (|0.37| ± 0.18 µm) compared to the SMY (|0.34| ± 0.16 µm, P <0.001). The mean values of vertical coma (Z<sub>3</sub> <sup>-1</sup>), vertical trefoil (Z<sub>3</sub> <sup>-3</sup>), and oblique trefoil (Z<sub>3</sub> <sup>3</sup>) differed between the two subgroups.</p><p><strong>Conclusion: </strong>Total RMS wave-front error increases with increasing myopia and astigmatism. Increasing myopia power does not show a systematic correlation with HOAs components. A weak systematic correlation is suggested between astigmatism direction and third-order aberrations.</p>","PeriodicalId":73096,"journal":{"name":"Frontiers in ophthalmology","volume":"5 ","pages":"1532931"},"PeriodicalIF":0.9000,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965624/pdf/","citationCount":"0","resultStr":"{\"title\":\"Associations between refractive error components and higher-order aberrations in simple myopia and compound myopic astigmatism.\",\"authors\":\"Sahar Mohaghegh, Shahram Bamdad, Haleh Kangari, Saeed Rahmani\",\"doi\":\"10.3389/fopht.2025.1532931\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>To investigate associations between refractive error components and higher-order aberrations (HOAs) in adult myopic subjects.</p><p><strong>Methods: </strong>A total of 1370 myopia right eyes, aged 18-40, were included in a cross-sectional study. Subjective cycloplegic refractions and distance aberrometry measured with a Shack-Hartmann device were analyzed. Zernike components of horizontal coma (Z<sub>3</sub> <sup>1</sup>), vertical coma (Z<sub>3</sub> <sup>-1</sup>), oblique trefoil (Z<sub>3</sub> <sup>3</sup>), vertical trefoil (Z<sub>3</sub> <sup>-3</sup>), spherical aberration, and total root-mean-square (RMS) wave-front error for 6 mm pupil were analyzed. Pearson's correlations were calculated between sphero-cylindrical components and HOAs based on vector analysis for the astigmatism axis. Total subjects were divided into two subgroups: simple myopia (SMY, 648 eyes) and compound myopic astigmatism (CMA, 722 eyes). HOAs were compared between the two subgroups.</p><p><strong>Results: </strong>Total RMS wave-front error correlates with spherical equivalent myopia (r = -0.1, P<0.05) and J45 (r = 0.1, P<0.001). J0 correlates positively with vertical coma (Z<sub>3</sub> <sup>-1</sup>) (r = 0.1 p <0.001) and negatively with oblique trefoil (Z<sub>3</sub> <sup>3</sup>) and vertical trefoil (Z<sub>3</sub> <sup>-3</sup>), (r = -0.1, p < 0.001; r = -0.1, P < 0.05). The total RMS wavefront-error was larger in the CMA (|0.37| ± 0.18 µm) compared to the SMY (|0.34| ± 0.16 µm, P <0.001). The mean values of vertical coma (Z<sub>3</sub> <sup>-1</sup>), vertical trefoil (Z<sub>3</sub> <sup>-3</sup>), and oblique trefoil (Z<sub>3</sub> <sup>3</sup>) differed between the two subgroups.</p><p><strong>Conclusion: </strong>Total RMS wave-front error increases with increasing myopia and astigmatism. Increasing myopia power does not show a systematic correlation with HOAs components. A weak systematic correlation is suggested between astigmatism direction and third-order aberrations.</p>\",\"PeriodicalId\":73096,\"journal\":{\"name\":\"Frontiers in ophthalmology\",\"volume\":\"5 \",\"pages\":\"1532931\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-03-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965624/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3389/fopht.2025.1532931\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/fopht.2025.1532931","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Associations between refractive error components and higher-order aberrations in simple myopia and compound myopic astigmatism.
Aim: To investigate associations between refractive error components and higher-order aberrations (HOAs) in adult myopic subjects.
Methods: A total of 1370 myopia right eyes, aged 18-40, were included in a cross-sectional study. Subjective cycloplegic refractions and distance aberrometry measured with a Shack-Hartmann device were analyzed. Zernike components of horizontal coma (Z31), vertical coma (Z3-1), oblique trefoil (Z33), vertical trefoil (Z3-3), spherical aberration, and total root-mean-square (RMS) wave-front error for 6 mm pupil were analyzed. Pearson's correlations were calculated between sphero-cylindrical components and HOAs based on vector analysis for the astigmatism axis. Total subjects were divided into two subgroups: simple myopia (SMY, 648 eyes) and compound myopic astigmatism (CMA, 722 eyes). HOAs were compared between the two subgroups.
Results: Total RMS wave-front error correlates with spherical equivalent myopia (r = -0.1, P<0.05) and J45 (r = 0.1, P<0.001). J0 correlates positively with vertical coma (Z3-1) (r = 0.1 p <0.001) and negatively with oblique trefoil (Z33) and vertical trefoil (Z3-3), (r = -0.1, p < 0.001; r = -0.1, P < 0.05). The total RMS wavefront-error was larger in the CMA (|0.37| ± 0.18 µm) compared to the SMY (|0.34| ± 0.16 µm, P <0.001). The mean values of vertical coma (Z3-1), vertical trefoil (Z3-3), and oblique trefoil (Z33) differed between the two subgroups.
Conclusion: Total RMS wave-front error increases with increasing myopia and astigmatism. Increasing myopia power does not show a systematic correlation with HOAs components. A weak systematic correlation is suggested between astigmatism direction and third-order aberrations.