喂养或繁殖：将能量供应与青春期发作联系起来的下丘脑机制。

IF 14.7 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-04-02 DOI:10.1016/j.neuron.2025.03.012

Alicia Sicardi, Daniela Fernandois, Vincent Prevot

引用次数: 0

摘要

哺乳动物的青春期开始需要足够的能量储存，但调节生殖的下丘脑神经元如何获得食物供应的信息尚不清楚。在这一期的《神经元》中，Goto等人1表明，下丘脑神经元表达agouti相关肽（饥饿传感器），控制kisspeptin神经元的成熟，kisspeptin神经元是繁殖的主要刺激物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Feed or breed: Hypothalamic mechanisms linking energy availability to puberty onset.

Puberty onset in mammals requires adequate energy stores, but how hypothalamic neurons regulating reproduction obtain information on food availability is unclear. In this issue of Neuron, Goto et al.¹ show that hypothalamic neurons expressing agouti-related peptides, which are hunger sensors, control the maturation of kisspeptin neurons, the principal stimulators of reproduction.

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.