【撤回】Etiasa对溃疡性结肠炎模型大鼠基质金属蛋白酶2和肿瘤坏死因子α表达的影响。

IF 3.4 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Molecular medicine reports Pub Date : 2025-06-01 Epub Date: 2025-04-04 DOI:10.3892/mmr.2025.13513
Jing-Wei Mao, Hai-Ying Tang, Xiao-Yan Tan, Ying-De Wang
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引用次数: 0

摘要

在这篇论文发表之后,一位关心的读者引起了编辑们的注意,在比较第998页图1和图2中的琼脂糖凝胶时,“第14天/第35天”和“第21天/第56天”实验中TNF - α数据的两对通道惊人地相似,尽管这些通道的方向相对相反。此外,图2中“第56天”实验的“E”和“C”通道中的MMP‑2蛋白带在外观上也非常相似。最后,在图3和图4所示的免疫荧光实验中,我们发现每个图中都有一对数据面板重叠,而且同一课题组在同一时间发表在《胃肠病学研究与实践》杂志上的另一篇论文中也出现了一些相同的数据面板。考虑到图1和图2中数据的明显异常,以及图3和图4中某些数据的重复使用,《分子医学报告》的编辑决定,由于对所呈现的数据缺乏信心,应从该杂志撤回这篇论文。作者被要求对这些担忧作出解释,但编辑部没有收到答复。对于由此给读者带来的不便,本刊编辑深表歉意。[分子医学报告]6:996‑1000,2012;DOI: 10.3892 / mmr.2012.1021]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Retracted] Effect of Etiasa on the expression of matrix metalloproteinase‑2 and tumor necrosis factor‑α in a rat model of ulcerative colitis.

Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that, in comparing the agarose gels featured in Figs. 1 and 2 on p. 998, two pairs of lanes for the TNF‑α data featured for the 'on day 14/on day 35' and 'on day 21/on day 56' experiments were strikingly similar, although the lanes were featured in reverse orientations relative to each other. Furthermore, MMP‑2 protein bands featured in Fig. 2 in the 'E' and 'C' lanes of the 'on day 56' experiments were also strikingly similar in appearance. Finally, concerning the immunofluorescence experiments shown in Figs. 3 and 4, one pair of data panels in each of the figures was found to be overlapping, and moreover, some of the same data panels also appeared in a figure in another paper written by the same research group that was published in the journal Gastroenterology Research and Practice at around the same time. In view of the apparent anomalies associated with the data in Figs. 1 and 2, and the re‑use of certain of the data in Figs. 3 and 4, the Editor of Molecular Medicine Reports has decided that this paper should be retracted from the Journal on the grounds of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [Molecular Medicine Reports 6: 996‑1000, 2012; DOI: 10.3892/mmr.2012.1021].

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来源期刊
Molecular medicine reports
Molecular medicine reports 医学-病理学
CiteScore
7.60
自引率
0.00%
发文量
321
审稿时长
1.5 months
期刊介绍: Molecular Medicine Reports is a monthly, peer-reviewed journal available in print and online, that includes studies devoted to molecular medicine, underscoring aspects including pharmacology, pathology, genetics, neurosciences, infectious diseases, molecular cardiology and molecular surgery. In vitro and in vivo studies of experimental model systems pertaining to the mechanisms of a variety of diseases offer researchers the necessary tools and knowledge with which to aid the diagnosis and treatment of human diseases.
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