Yi-Sa Zhao, Jie Huang, Xingjian Yang, Weqiang Wang, Deng-Guang Yu, Hua He, Ping Liu, Kewei Du
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Electrospun nanofibers and their application as sensors for healthcare.
Electrospinning is a type of electrohydrodynamics that utilizes high-voltage electrostatic force to stretch a polymer solution into nanofibers under the influence of an electric field, with most of the fibers falling onto a collector. This technology is favored by researchers across various fields due to its simple and inexpensive device for producing nanofibers in a straightforward manner. Nanofibers prepared through electrospinning have a high specific surface area and high porosity. Electrospinning technology shows extensive potential, especially within biomedical sensors. This article provides a systematic overview of the factors influencing electrospinning, the parameters of the electrospinning process, the types of electrospun nanofibers, and the applications of electrospinning technology in the field of sensors, including wearable sensors, pressure sensors, and glucose sensors. The paper summarizes the research progress in this field and points out the direction of development for electrospinning technology, as well as the future challenges.
期刊介绍：
The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs.
In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.
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