年轻患者屈光手术后干眼病的治疗：一项基于人群的研究

IF 2.8 3区医学 Q1 OPHTHALMOLOGY

Eye Pub Date : 2025-04-03 DOI:10.1038/s41433-025-03783-5

Itay Nitzan, Dan Heller, Clara C Chan, Michael Mimouni, Margarita Safir

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引用次数: 0

摘要

目的：了解青少年屈光手术后干眼病（DED）润滑滴眼液治疗需求。方法：本研究涉及2011年至2019年期间接受系统医学评估的16-20岁以色列青少年和年轻人。根据医疗记录确定屈光手术状态。在三年的时间里，通过计算机化的配药数据监测润滑眼药水的使用情况。采用按性别分层并根据社会人口变量进行调整的回归模型。结果：591,919例患者（57.4%为男性，平均年龄17.2岁）中，4571例（0.8%）接受了屈光手术。使用润滑滴眼液的男性比例为1.4%，女性为2.3%，屈光手术组的比例更高(男性为4.0%，女性为1.4%;9.5%，女性为2.3%；p结论：屈光手术后的年轻患者在手术后一年多的时间里更有可能需要DED润滑眼药水。

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Dry eye disease treatment following refractive surgery among young patients: a population-based study.

Objectives: To evaluate the demand for dry eye disease (DED) lubricating eye drop treatment following refractive surgery among young patients.

Methods: This study involved Israeli adolescents and young adults aged 16-20 years who underwent systematic medical evaluations from 2011 to 2019. Refractive surgery status was determined based on medical records. Lubricating eye drop usage was monitored through computerized dispensation data over a three-year period. Regression models, stratified by sex and adjusted for sociodemographic variables, were used.

Results: Among 591,919 individuals (57.4% male, mean age 17.2 years), 4571 (0.8%) underwent refractive surgery. Lubricating eye drop usage was observed in 1.4% of men and 2.3% of women, with higher proportions in the refractive surgery group (4.0% vs. 1.4% and 9.5% vs. 2.3% for men and women, respectively; p < 0.001). Adjusted odds ratios (aORs) for increased DED treatment durations in men were 2.34 (95% CI 1.94-2.83) for ≤3 months, 5.22 (95% CI 3.43-7.94) for 3 to 12 months, and 5.79 (95% CI 3.69-9.09) for over 12 months. For women, aORs were 3.68 (95% CI 2.50-5.41) for ≤3 months, 6.06 (95% CI 2.50-14.73) for 3-12 months, and 11.57 (95% CI 4.74-28.25) for over 12 months.

Conclusions: Young patients after refractive surgery are significantly more likely to require DED lubricating eye drops for over a year following the procedure.

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来源期刊

Eye 医学-眼科学

CiteScore

6.40

自引率

5.10%

发文量

481

审稿时长

3-6 weeks

期刊介绍： Eye seeks to provide the international practising ophthalmologist with high quality articles, of academic rigour, on the latest global clinical and laboratory based research. Its core aim is to advance the science and practice of ophthalmology with the latest clinical- and scientific-based research. Whilst principally aimed at the practising clinician, the journal contains material of interest to a wider readership including optometrists, orthoptists, other health care professionals and research workers in all aspects of the field of visual science worldwide. Eye is the official journal of The Royal College of Ophthalmologists. Eye encourages the submission of original articles covering all aspects of ophthalmology including: external eye disease; oculo-plastic surgery; orbital and lacrimal disease; ocular surface and corneal disorders; paediatric ophthalmology and strabismus; glaucoma; medical and surgical retina; neuro-ophthalmology; cataract and refractive surgery; ocular oncology; ophthalmic pathology; ophthalmic genetics.