胶原血管病相关的间质性肺炎与18f -氟雌二醇的积累。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-04-07 DOI:10.1097/RLU.0000000000005743

Sumika Yasumura, Kanae K Miyake, Yoichi Shimizu, Tomomi Nobashi, Yuji Nakamoto

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引用次数: 0

摘要

18f -氟雌二醇（18F-FES）是一种PET放射性示踪剂，与表达ER的细胞核中的雌激素受体（ER）结合，在临床上越来越多地用于乳腺癌患者，以观察病变中ER的表达。虽然18F-FES积累通常是特异性的，但辐射诱发的肺炎可能产生假阳性结果，但其潜在机制在很大程度上仍不清楚。在这里，我们报告了一位72岁的女性，已知胶原血管病相关的间质性肺炎，18F-FES- pet /CT显示18F-FES积累，以调查疑似复发性乳腺癌。

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Collagen Vascular Disease-Associated Interstitial Pneumonia With Accumulation of 18F-fluoroestradiol.

18F-fluoroestradiol (18F-FES) is a PET radiotracer that binds to the estrogen receptor (ER) in the nucleus of ER-expressing cells and is increasingly used clinically in breast cancer patients to visualize ER expression in lesions. Although 18F-FES accumulation is generally specific, radiation-induced pneumonitis can produce false-positive results, but the underlying mechanisms remain largely unclear. Here, we report the case of a 72-year-old woman with known collagen vascular disease-associated interstitial pneumonia and the accumulation of 18F-FES on 18F-FES-PET/CT, which was conducted to investigate suspected recurrent breast cancer.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.