骨未成熟患者股骨远端感染初级重建后使用生物可膨胀假体成功保肢手术:一例报告。

IF 2.5 3区 医学 Q3 ONCOLOGY
Jan Lesensky, Ana C Belzarena, Michal Benes
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引用次数: 0

摘要

背景:假体周围感染是因肿瘤骨科疾病而接受治疗的骨骼尚未发育成熟的患者的一种严重并发症。翻修手术的重建方法往往有限,许多病例仍然需要截肢:在本报告中,我们介绍了在一名青少年女性患者的翻修手术第二阶段中使用生物可扩张 MUTARS® BioXpand 假体的独特经验。最初,该患者在切除高位股骨远端骨肉瘤后使用传统假体进行重建,但六个月后出现深度感染。在两阶段翻修手术中,感染被成功根除,但胫骨近端部位的生长潜力也因此丧失。通过应用生物可扩张内假体,患者的肢体长度恢复了最初的 5 厘米差异,骨量增加了 8 厘米。在最后一次复诊时,患者已经可以完全负重,临床效果极佳,没有感染或肿瘤复发的迹象:结论:这一成功的肢体修复手术表明,生物可扩张内假体可作为骨骼不成熟者翻修手术中可行且有效的重建选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Successful limb-salvage procedure using a bioexpandable prosthesis after infected primary reconstruction of the distal femur in a skeletally immature patient: a case report.

Background: Periprosthetic infections pose a devastating complication in skeletally immature patients treated for an orthopaedic oncological condition. Reconstructive approaches to revision procedures are often limited, and many cases still require amputation.

Case presentation: In this report, we present our unique experience with the bio-expandable MUTARS® BioXpand prosthesis, utilized during the second stage of a revision surgery in an adolescent female patient. Initially, the patient underwent reconstruction using a conventional endoprosthesis following the resection of a high-grade distal femur osteosarcoma; however, she developed a deep infection six months later. During a two-stage revision procedure, the infection was successfully eradicated at the cost of loss of growth potential at also the site of proximal tibia. The initial 5 cm limb-length discrepancy was restored through the application of bioexpandable endoprosthesis, which allowed for an 8 cm gain in bone stock. At the last follow-up appointment, the patient was fully weight-bearing and demonstrated excellent clinical outcomes, with no evidence of infection or tumor recurrence.

Conclusion: This successful limb-salvage procedure indicates that bioexpandable endoprosthesis may serve as a viable and effective reconstructive option in revision surgery for skeletally immature individuals.

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来源期刊
CiteScore
4.70
自引率
15.60%
发文量
362
审稿时长
3 months
期刊介绍: World Journal of Surgical Oncology publishes articles related to surgical oncology and its allied subjects, such as epidemiology, cancer research, biomarkers, prevention, pathology, radiology, cancer treatment, clinical trials, multimodality treatment and molecular biology. Emphasis is placed on original research articles. The journal also publishes significant clinical case reports, as well as balanced and timely reviews on selected topics. Oncology is a multidisciplinary super-speciality of which surgical oncology forms an integral component, especially with solid tumors. Surgical oncologists around the world are involved in research extending from detecting the mechanisms underlying the causation of cancer, to its treatment and prevention. The role of a surgical oncologist extends across the whole continuum of care. With continued developments in diagnosis and treatment, the role of a surgical oncologist is ever-changing. Hence, World Journal of Surgical Oncology aims to keep readers abreast with latest developments that will ultimately influence the work of surgical oncologists.
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