{"title":"巨细胞动脉炎(Horton's disease)的诊断与治疗最新进展。","authors":"Edwin Curraj, Camillo Ribi","doi":"10.53738/REVMED.2025.21.912.648","DOIUrl":null,"url":null,"abstract":"<p><p>Giant cell arteritis (GCA, Horton's disease) is a subacute vasculitis of large-size arteries. GCA affects individuals above 50 years and its frequency increases with age. The key elements for diagnosis are clinical presentation, elevated inflammatory markers, imaging, and histology. Temporal artery biopsy is the gold standard for confirming GCA, but is gradually being replaced by non-invasive imaging techniques such as Doppler ultrasound and positron emission tomography. While corticosteroids remain the cornerstone of treatment, new therapies are helping to reduce their dosage and duration of use. In this review, the key aspects of diagnosing and treating GCA, based on the latest recommendations are discussed in this article.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"648-653"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Latest advances in diagnosis and therapy of giant cell arteritis (Horton's disease)].\",\"authors\":\"Edwin Curraj, Camillo Ribi\",\"doi\":\"10.53738/REVMED.2025.21.912.648\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Giant cell arteritis (GCA, Horton's disease) is a subacute vasculitis of large-size arteries. GCA affects individuals above 50 years and its frequency increases with age. The key elements for diagnosis are clinical presentation, elevated inflammatory markers, imaging, and histology. Temporal artery biopsy is the gold standard for confirming GCA, but is gradually being replaced by non-invasive imaging techniques such as Doppler ultrasound and positron emission tomography. While corticosteroids remain the cornerstone of treatment, new therapies are helping to reduce their dosage and duration of use. In this review, the key aspects of diagnosing and treating GCA, based on the latest recommendations are discussed in this article.</p>\",\"PeriodicalId\":21286,\"journal\":{\"name\":\"Revue medicale suisse\",\"volume\":\"21 912\",\"pages\":\"648-653\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revue medicale suisse\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.53738/REVMED.2025.21.912.648\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue medicale suisse","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53738/REVMED.2025.21.912.648","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
[Latest advances in diagnosis and therapy of giant cell arteritis (Horton's disease)].
Giant cell arteritis (GCA, Horton's disease) is a subacute vasculitis of large-size arteries. GCA affects individuals above 50 years and its frequency increases with age. The key elements for diagnosis are clinical presentation, elevated inflammatory markers, imaging, and histology. Temporal artery biopsy is the gold standard for confirming GCA, but is gradually being replaced by non-invasive imaging techniques such as Doppler ultrasound and positron emission tomography. While corticosteroids remain the cornerstone of treatment, new therapies are helping to reduce their dosage and duration of use. In this review, the key aspects of diagnosing and treating GCA, based on the latest recommendations are discussed in this article.
期刊介绍:
Destinée aux professionnels de santé, la plateforme revmed.ch regroupe la version électronique de la Revue Médicale Suisse et les applications de formation et d"aide à la prise de décision eRMS. La eRMS est le fruit d’une large collaboration entre institutions et praticiens de Suisse romande.