The plant proteome delivers from discovery to innovation.

The field of mass spectrometry (MS)-based proteomics is rapidly advancing with technological and computational improvements, including leveraging the power of artificial intelligence (AI) to drive innovation. Such innovation has been particularly apparent in human disease research, where the intersection of these disciplines has pioneered a new age of disease diagnostics and pharmaceutical discovery. However, applications within plant sciences remains woefully under-represented and yet provides exceptional promise and potential to support new, interdisciplinary areas of research. Timely and novel examples of proteomics advancing plant science encompass biotechnology, climatic resiliency, agricultural production systems, and disease management. Herein, we propose new scientific avenues that leverage the power of proteomics and AI within plant science research to drive new discoveries and innovation.