Matt R Judah, Hannah C Hamrick, Benjamin Swanson, Morgan S Middlebrooks, Grant S Shields
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引用次数: 0
摘要
研究表明,广泛性焦虑症(GAD)症状与对负面图像的晚期正电位(LPP)反应有关,表明注意力更集中。焦虑敏感性(AS)和不确定性不耐受性(IU)是 GAD 易感性的认知因素,可能会被负面刺激激活,从而解释为什么 LPP 与 GAD 症状相关。我们研究了 AS 和 IU 是否可以解释 LPP 与 GAD 症状之间的关联。87 名年轻成年人(77% 为女性)观看了 60 幅负面图像和 60 幅中性图像。我们使用频繁主义和贝叶斯方法对 LPP 进行了研究。结果显示,LPP 通过 AS 和 IU 对 GAD 症状产生了独特的间接影响。这两种间接效应都不强,而且无论使用频数分析法还是贝叶斯分析法,也无论使用基于残差的分数还是差异分数来量化 LPP,间接效应都是存在的。间接效应不仅能预测 GAD 症状,还能预测社交焦虑和抑郁,这与 AS 和 IU 在跨诊断易感性中的作用是一致的。研究结果表明,AS 和 IU 可以解释对负面刺激的关注不仅与 GAD 症状有关,而且还与其他内化症状有关。
Anxiety Sensitivity and Intolerance of Uncertainty Uniquely Explain the Association of the Late Positive Potential With Generalized Anxiety Disorder Symptoms.
Studies suggest that generalized anxiety disorder (GAD) symptoms are related to late positive potential (LPP) responses to negative images, suggesting greater attention. Anxiety sensitivity (AS) and intolerance of uncertainty (IU) are cognitive factors in GAD vulnerability that may be activated by negative stimuli, thereby explaining why the LPP and GAD symptoms are related. We examined whether AS and IU explain the association of the LPP with GAD symptoms. Eighty-seven (77% women) young adults viewed 60 negative and 60 neutral images. The LPP was examined using both frequentist and Bayesian approaches. This revealed unique indirect effects of the LPP on GAD symptoms through AS and IU. Neither indirect effect was stronger, and the indirect effects were present regardless of using frequentist or Bayesian analyses or quantifying the LPP using residual-based scores or difference scores. The indirect effects predicted not only GAD symptoms but social anxiety and depression as well, consistent with the role of AS and IU in transdiagnostic vulnerability. The findings support AS and IU as links that explain how attention to negative stimuli is related not only to GAD symptoms but to other internalizing symptoms as well.
期刊介绍:
Founded in 1964, Psychophysiology is the most established journal in the world specifically dedicated to the dissemination of psychophysiological science. The journal continues to play a key role in advancing human neuroscience in its many forms and methodologies (including central and peripheral measures), covering research on the interrelationships between the physiological and psychological aspects of brain and behavior. Typically, studies published in Psychophysiology include psychological independent variables and noninvasive physiological dependent variables (hemodynamic, optical, and electromagnetic brain imaging and/or peripheral measures such as respiratory sinus arrhythmia, electromyography, pupillography, and many others). The majority of studies published in the journal involve human participants, but work using animal models of such phenomena is occasionally published. Psychophysiology welcomes submissions on new theoretical, empirical, and methodological advances in: cognitive, affective, clinical and social neuroscience, psychopathology and psychiatry, health science and behavioral medicine, and biomedical engineering. The journal publishes theoretical papers, evaluative reviews of literature, empirical papers, and methodological papers, with submissions welcome from scientists in any fields mentioned above.