印度早产儿代谢性骨病的发病率和危险因素：一项前瞻性观察研究

IF 1.7 4区医学 Q2 PEDIATRICS

Indian pediatrics Pub Date : 2025-04-03 DOI:10.1007/s13312-025-00051-3

S B Mithun Krishna, Jitendra Meena, Jogender Kumar, Kanya Mukhopadhyay, Praveen Kumar

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引用次数: 0

摘要

目的：探讨早产儿代谢性骨病（MBDP）的发病率及危险因素。方法：采用血清钙、磷和碱性磷酸酶水平对妊娠≤33周出生的婴儿进行MBDP筛查。筛查从3-6周开始，并按照指示重复，直到矫正年龄3个月。比较了有和没有MBDP的婴儿的饲料量、营养补充和发病率数据。结果：153例患儿中，中度MBDP 22例（14.4%），重度MBDP 28例（18.3%）。低出生体重与严重MBDP独立相关（P-0.009）。结论：在我们的队列中，近40%的早产儿患有中度至重度MBDP。

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Incidence and Risk Factors for Metabolic Bone Disease of Prematurity in Indian Infants: A Prospective Observational Study.

Purpose: To assess the incidence and risk factors for metabolic bone disease of prematurity (MBDP).

Methods: Infants born at ≤ 33 weeks' gestation were screened for MBDP using serum calcium, phosphorus, and alkaline phosphatase levels. Screening began at 3-6 weeks and was repeated as indicated until three months of corrected age. Feed volume, nutrient supplementation, and morbidity data were compared between the infants with and without MBDP.

Results: Among the 153 infants, 22 (14.4%) had moderate MBDP and 28 (18.3%) had severe MBDP. Lower birth weight was independently associated with severe MBDP (P-0.009).

Conclusions: Nearly 40% of the preterm infants in our cohort had moderate-to-severe MBDP.

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来源期刊

Indian pediatrics 医学-小儿科

CiteScore

3.30

自引率

8.70%

发文量

344

审稿时长

3-8 weeks

期刊介绍： The general objective of Indian Pediatrics is "To promote the science and practice of Pediatrics." An important guiding principle has been the simultaneous need to inform, educate and entertain the target audience. The specific key objectives are: -To publish original, relevant, well researched peer reviewed articles on issues related to child health. -To provide continuing education to support informed clinical decisions and research. -To foster responsible and balanced debate on controversial issues that affect child health, including non-clinical areas such as medical education, ethics, law, environment and economics. -To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible and enjoyable to read.