结节病的罕见表现:非肺部累及病例。

IF 1.3 Q4 RHEUMATOLOGY
Gokhan Koker, Lutfullah Zahit Koc, Sevgi Gulsen, Sibel Bakirci, Cengiz Aldemir
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引用次数: 0

摘要

结节病是一种以病因不明的非干酪化肉芽肿为特征的炎症性疾病,典型表现为肺部受累。然而,没有肺部表现的表现是非常罕见的。我们报告了2例不寻常的结节病,但没有肺部受累。60岁男性,左手慢性关节疼痛和肿胀。尽管反复的医院就诊和不确定的评估,通过组织病理学检查确认肉芽肿性腱鞘炎。排除全身受累,患者对皮质类固醇治疗反应良好。女性,36岁,左手皮下结节持续6年。活检证实非干酪样肉芽肿符合结节病。尽管没有肺部发现,但系统筛查未发现进一步的累及。病灶内皮质类固醇治疗有显著改善。虽然结节病通常表现为肺部受累,但没有肺部表现的病例是罕见的。我们的病例突出了诊断的挑战和延迟识别这样的表现。提高对非典型表现的认识对于及时诊断和预防潜在的全身并发症至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rare Presentations of Sarcoidosis: Cases of Non-Pulmonary Involvement.

Sarcoidosis, an inflammatory disease characterized by non-caseating granulomas of unknown etiology, typically manifests with pulmonary involvement. However, presentations without pulmonary manifestations are exceedingly rare. We present 2 cases illustrating unusual presentations of sarcoidosis without pulmonary involvement. A 60-year-old male presented with chronic joint pain and swelling in the left hand. Despite recurrent hospital visits and inconclusive evaluations, granulomatous tenosynovitis was confirmed through histopathological examination. Systemic involvement was ruled out, and the patient responded well to corticosteroid therapy. A 36-year-old female exhibited persistent subcutaneous nodules on the left hand for 6 years. A biopsy confirmed non-caseating granulomas consistent with sarcoidosis. Despite the absence of pulmonary findings, systemic screening revealed no further involvement. Intralesional corticosteroid therapy yielded significant improvement. Although sarcoidosis typically presents with pulmonary involvement, cases without pulmonary manifestations are rare. Our cases highlight the diagnostic challenges and delayed recognition of such presentations. Increased awareness of atypical presentations is crucial for timely diagnosis and management to prevent potential systemic complications.

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