Th17细胞在心血管疾病中的作用

IF 2.7 3区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Cell Biochemistry and Function Pub Date : 2025-04-03 DOI:10.1002/cbf.70069

Ke Yang, Qianqian Liu, Aodi Fan, Hanqing Lin, Xizheng Wang, Tianyi Cui, Guanwei Fan, Lan Li

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引用次数: 0

摘要

最近的研究表明，Th17细胞及其细胞因子IL-17与动脉粥样硬化、心肌梗死、心肌炎和心律失常等多种心血管疾病之间存在密切联系。此外，Th17细胞信号传导可能是心血管疾病的关键因素。本文就Th17信号的来源、功能、调控及其在心血管疾病中的作用等方面的研究进展进行综述。对Th17的研究将提出更具体的策略来操纵这些功能。因此，有效的治疗心血管疾病和未来的临床治疗将是可能的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Th17 Cells in Cardiovascular Disease

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Th17 Cells in Cardiovascular Disease

Recent research has shown a strong link between Th17 cells and their cytokine IL-17, and various cardiovascular diseases such as atherosclerosis, myocardial infarction, myocarditis, and arrhythmia. Moreover, Th17 cell signalling is likely to be a key factor in cardiovascular disease. Here, we summarize recent advances in the source, function, regulation, and the effects of Th17 signaling in cardiovascular disease. Research on Th17 will suggest more specific strategies to manipulate these functions. Thus, effective treatment of cardiovascular disease and future clinical treatment will be possible.

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来源期刊

Cell Biochemistry and Function 生物-生化与分子生物学

CiteScore

6.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Cell Biochemistry and Function publishes original research articles and reviews on the mechanisms whereby molecular and biochemical processes control cellular activity with a particular emphasis on the integration of molecular and cell biology, biochemistry and physiology in the regulation of tissue function in health and disease. The primary remit of the journal is on mammalian biology both in vivo and in vitro but studies of cells in situ are especially encouraged. Observational and pathological studies will be considered providing they include a rational discussion of the possible molecular and biochemical mechanisms behind them and the immediate impact of these observations to our understanding of mammalian biology.