通过多孔水凝胶膜的屈曲微通道创建的芯片上器官平台。抛光工艺。7/2025)

IF 6.4 3区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Advanced Materials Technologies Pub Date : 2025-04-04 DOI:10.1002/admt.202570037

Riku Takahashi, Aya Tanaka, Tomoki Saito, Shinya Ohashi, Manabu Muto, Masumi Yamaguchi

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引用次数: 0

摘要

在文章编号2401468中，Riku Takahashi及其同事提出了一种通过将水凝胶孔隙化与薄膜形状控制相结合来制造可渗透微通道的方法。这种方法在保持合成聚合物优异机械性能的同时提高了渗透率。开发的微通道系统支持血管内皮细胞培养，作为屏障功能评估、多种通道制造和共培养系统开发的血管芯片平台。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Organ-On-A-Chip Platforms Created Through Buckled Microchannels of Porous Hydrogel Films (Adv. Mater. Technol. 7/2025)

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Organ-On-A-Chip Platforms Created Through Buckled Microchannels of Porous Hydrogel Films (Adv. Mater. Technol. 7/2025)

Organ-on-a-Chip Platforms

In article number 2401468, Riku Takahashi and co-workers present a method for fabricating permeable microchannels by integrating hydrogel porosification with thin-film shape control. This approach enhances permeability while preserving the excellent mechanical properties of synthetic polymers. The developed microchannel system supports vascular endothelial cell culture, functioning as a vessel-on-a-chip platform for barrier function assessment, diverse channel fabrication, and co-culture system development.

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来源期刊

Advanced Materials Technologies Materials Science-General Materials Science

CiteScore

10.20

自引率

4.40%

发文量

566

期刊介绍： Advanced Materials Technologies Advanced Materials Technologies is the new home for all technology-related materials applications research, with particular focus on advanced device design, fabrication and integration, as well as new technologies based on novel materials. It bridges the gap between fundamental laboratory research and industry.