Chiyoung Lee PhD, RN , Juyoung Park PhD, MSW , Mindy Fain MD , James E. Galvin MD, MPH , Lindsey Park BS , Hyochol Ahn PhD, APRN, ANP-BC, FAAN
{"title":"经颅直流电刺激对老年阿尔茨海默病及相关痴呆患者疼痛缓解的即时和长期影响:一项初步研究","authors":"Chiyoung Lee PhD, RN , Juyoung Park PhD, MSW , Mindy Fain MD , James E. Galvin MD, MPH , Lindsey Park BS , Hyochol Ahn PhD, APRN, ANP-BC, FAAN","doi":"10.1016/j.gerinurse.2025.03.025","DOIUrl":null,"url":null,"abstract":"<div><div>We simultaneously assessed the impact of transcranial direct current stimulation (tDCS) on mitigating both self-reported pain and pain behaviors to more objectively explore its effects in older adults with Alzheimer's disease and related dementias. The analysis investigated 40 participants randomly (1:1) subjected to active and sham tDCS for 20 min on 5 consecutive days<em>.</em> Multi-group latent transition analysis enabled the simultaneous evaluation of both pain domains in a single model and analysis of their changes as a function of intervention exposure by modeling the transition probabilities of latent classes and comparing these changes between groups. Two pain categories (“high pain” and “low pain”) were identified based on the numeric rating scale and mobilization–observation–behavior–intensity–dementia scale scores. Overall, tDCS demonstrated better effects in helping participants transition to a “low pain” status during and after the intervention (∼3 months) compared with sham stimulation, demonstrating its immediate and enduring effects.</div></div>","PeriodicalId":56258,"journal":{"name":"Geriatric Nursing","volume":"63 ","pages":"Pages 138-146"},"PeriodicalIF":2.5000,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Immediate and long-term effects of transcranial direct current stimulation on pain relief in older adults with Alzheimer's disease and related dementias: A pilot study\",\"authors\":\"Chiyoung Lee PhD, RN , Juyoung Park PhD, MSW , Mindy Fain MD , James E. Galvin MD, MPH , Lindsey Park BS , Hyochol Ahn PhD, APRN, ANP-BC, FAAN\",\"doi\":\"10.1016/j.gerinurse.2025.03.025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We simultaneously assessed the impact of transcranial direct current stimulation (tDCS) on mitigating both self-reported pain and pain behaviors to more objectively explore its effects in older adults with Alzheimer's disease and related dementias. The analysis investigated 40 participants randomly (1:1) subjected to active and sham tDCS for 20 min on 5 consecutive days<em>.</em> Multi-group latent transition analysis enabled the simultaneous evaluation of both pain domains in a single model and analysis of their changes as a function of intervention exposure by modeling the transition probabilities of latent classes and comparing these changes between groups. Two pain categories (“high pain” and “low pain”) were identified based on the numeric rating scale and mobilization–observation–behavior–intensity–dementia scale scores. Overall, tDCS demonstrated better effects in helping participants transition to a “low pain” status during and after the intervention (∼3 months) compared with sham stimulation, demonstrating its immediate and enduring effects.</div></div>\",\"PeriodicalId\":56258,\"journal\":{\"name\":\"Geriatric Nursing\",\"volume\":\"63 \",\"pages\":\"Pages 138-146\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-04-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Geriatric Nursing\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0197457225001144\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Geriatric Nursing","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0197457225001144","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
Immediate and long-term effects of transcranial direct current stimulation on pain relief in older adults with Alzheimer's disease and related dementias: A pilot study
We simultaneously assessed the impact of transcranial direct current stimulation (tDCS) on mitigating both self-reported pain and pain behaviors to more objectively explore its effects in older adults with Alzheimer's disease and related dementias. The analysis investigated 40 participants randomly (1:1) subjected to active and sham tDCS for 20 min on 5 consecutive days. Multi-group latent transition analysis enabled the simultaneous evaluation of both pain domains in a single model and analysis of their changes as a function of intervention exposure by modeling the transition probabilities of latent classes and comparing these changes between groups. Two pain categories (“high pain” and “low pain”) were identified based on the numeric rating scale and mobilization–observation–behavior–intensity–dementia scale scores. Overall, tDCS demonstrated better effects in helping participants transition to a “low pain” status during and after the intervention (∼3 months) compared with sham stimulation, demonstrating its immediate and enduring effects.
期刊介绍:
Geriatric Nursing is a comprehensive source for clinical information and management advice relating to the care of older adults. The journal''s peer-reviewed articles report the latest developments in the management of acute and chronic disorders and provide practical advice on care of older adults across the long term continuum. Geriatric Nursing addresses current issues related to drugs, advance directives, staff development and management, legal issues, client and caregiver education, infection control, and other topics. The journal is written specifically for nurses and nurse practitioners who work with older adults in any care setting.