Mucinous Syringometaplasia in the Inguinal Region: Case Report and Literature Review.

Abstract: A 66-year-old man presented with a pedunculated papule measuring 9.0 mm in the left inguinal region. Excision was performed based on the clinical hypotheses of soft fibroma and pyogenic granuloma. Histopathologic evaluation demonstrated invagination of the epidermis, with a tubular tortuous path showing the presence of squamous cells and goblet cells rich in mucin, and adjacent epithelium showing acanthosis, papillomatosis, and hyperkeratosis, with a diagnosis of mucinous syringometaplasia. This is a rare entity, with 19 cases reported to date, including the present case, usually clinically diagnosed as a viral wart or basal cell carcinoma, with no cases of recurrence reported after complete excision.