桥本甲状腺炎-名字有什么关系?

IF 2.4 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM
Mikhail Khachaturov, Dimitrios G Goulis, Petros Perros
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引用次数: 0

摘要

桥本甲状腺炎(HT)是世界上最常见的自身免疫性内分泌疾病,年发病率为每1000人中0.3-1.5人,患病率为总人口的8%。文献中至少出现了9个表示HT的术语,这些术语被用作同义词或描述与HT密切相关的疾病。此外,HT的定义各不相同,一些参数在诊断中的作用仍不清楚。此外,专家经常使用“甲状腺炎”一词来描述甲状腺状态的三期演变(甲状腺毒症、甲状腺功能减退和甲状腺功能亢进),不仅在某些形式的激素治疗后发生,而且在其他原因的甲状腺炎症中也会发生。本文提出了解决命名问题的新方法。首先,我们应该放弃“桥本”这个名字,以跟上最近的趋势。留下的空白可以用已经使用的术语“自身免疫性甲状腺炎”或“自身免疫性甲状腺疾病”来代替。在我们之间以及与患者的交流中,必须尽可能提供这些术语的背景,说明它们是否适用于甲状腺状态、甲状腺肿的存在与否、甲状腺自身抗体、影像学、细胞学/组织学、流行病学或病因学。其次,使用甲状腺激素治疗甲状腺功能正常患者的潜在危害可以通过以下方式减少:按照现行指南,避免对无症状的甲状腺功能正常患者进行甲状腺自身抗体检测或甲状腺显像;当证据仅基于调查结果(如抗体阳性或显像)时,不鼓励使用“疾病”一词。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hashimoto's thyroiditis- What's in a name?

Hashimoto's thyroiditis (HT) is the most common autoimmune endocrine disease worldwide with an annual incidence of 0.3-1.5 per 1000 people and a prevalence of 8% of the general population. At least nine terms appear in the literature denoting HT, which are used as synonyms or are terms describing disorders closely related to HT. Moreover, the definitions of HT vary, and the role of several parameters in making a diagnosis remains unclear. Furthermore, the term "thyroiditis" is often used among experts to describe the triphasic evolution in thyroid status (thyrotoxicosis, hypothyroidism, and euthyroidism) that can occur not only after some forms of HT but also in other causes of thyroid inflammation. The present work proposes novel approaches for the nomenclature problems. Firstly, we should abandon the eponym "Hashimoto" in keeping with recent trends. The void left can be replaced by the terms "autoimmune thyroiditis" or "autoimmune thyroid disease", which are already in use. In communicating among ourselves and with patients, it is imperative and good practice to provide, whenever possible, context to these terms by specifying whether they apply to thyroid status, presence or absence of goiter, thyroid autoantibodies, imaging, cytology/histology, epidemiology, or etiology. Secondly, the considerable potential harm associated with treating euthyroid people with thyroid hormones could be curtailed by avoiding testing for thyroid autoantibodies or performing thyroid imaging in asymptomatic euthyroid patients following the current guidelines and by discouraging the use of the word "disease" when the evidence is based only on results of investigations, such as positive antibodies, or imaging.

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来源期刊
CiteScore
5.90
自引率
0.00%
发文量
76
审稿时长
6-12 weeks
期刊介绍: Hormones-International Journal of Endocrinology and Metabolism is an international journal published quarterly with an international editorial board aiming at providing a forum covering all fields of endocrinology and metabolic disorders such as disruption of glucose homeostasis (diabetes mellitus), impaired homeostasis of plasma lipids (dyslipidemia), the disorder of bone metabolism (osteoporosis), disturbances of endocrine function and reproductive capacity of women and men. Hormones-International Journal of Endocrinology and Metabolism particularly encourages clinical, translational and basic science submissions in the areas of endocrine cancers, nutrition, obesity and metabolic disorders, quality of life of endocrine diseases, epidemiology of endocrine and metabolic disorders.
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