欧洲狍子(Capreolus capreolus)的氟斑牙:回顾氟化颊齿珐琅质的病理变化以及受影响牙齿的异常磨损模式。

IF 1.8 4区 医学 Q2 ANATOMY & MORPHOLOGY
Uwe Kierdorf, Horst Kierdorf
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引用次数: 0

摘要

本文综述了来自人为氟化物排放污染地区的欧洲狍下颌颊恒牙釉质的病理变化及其后遗症。氟鹿牙釉质的主要(发育)变化是低矿化和微结构畸变,包括牙釉质发育不全。低矿化氟牙釉质在出牙时呈白色不透明,在出牙后染色。而且容易过度磨损和机械损坏,导致后牙釉质损伤。这些后发病变在形态学上可与发育不全明显区分。由于氟质牙釉质矿化受损,受影响的颊牙缺乏通常存在于咬合表面的突出牙釉质脊。氟斑牙的严重程度通常在更严重氟牙列的下颌颊恒牙之间有所不同。恒前磨牙和第三磨牙表现出明显的病理变化,第一磨牙基本不受影响,第二磨牙受氟化改变的影响较小。这些差异与产前和产后早期的保护机制(胎盘屏障和牛奶-血液对氟化物的屏障)有关,这些机制可以防止来自氟化物污染栖息地的个体在M1和部分M2冠形成期间血浆氟化物水平过高。对严重氟斑牙患者颊牙早期形成和晚期形成牙本质氟化物含量的观察支持这一假设。欧洲狍的研究结果构成了目前对野生反刍动物物种氟斑牙症最全面的表征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dental fluorosis in the European roe deer (Capreolus capreolus): A review of the pathological changes in the enamel of fluorotic cheek teeth and the abnormal pattern of dental wear in affected dentitions.

This article reviews the pathological changes in the enamel of permanent mandibular cheek teeth and their sequelae in European roe deer from regions polluted by anthropogenic fluoride emissions. The primary (developmental) changes of fluorotic roe deer enamel are hypomineralization and microstructural aberrations, including enamel hypoplasia. The hypomineralized fluorotic enamel is whitish-opaque on eruption and gets stained following tooth eruption. Moreover, it is prone to excessive wear and mechanical breakdown, resulting in posteruptive enamel lesions. These posteruptive lesions can morphologically clearly be distinguished from hypoplastic defects. Due to the impaired mineralization of fluorotic enamel, affected cheek teeth lack the prominent enamel ridges normally present on the occlusal surface. The severity of dental fluorosis typically varies among the permanent mandibular cheek teeth of more severely fluorotic dentitions. While the permanent premolars and the third molar show marked pathological changes, the first molar is largely unaffected, and the second molar is less affected by fluorotic alterations. These differences have been related to protective mechanisms (placental barrier and milk-blood barrier to fluoride) operating during prenatal and early postnatal life that prevent excessive plasma fluoride levels during crown formation of the M1 and partly also of the M2 in individuals from fluoride-polluted habitats. Observations on the fluoride content of early-formed and late-formed dentin of cheek teeth from individuals with severe dental fluorosis support this hypothesis. The findings in the European roe deer constitute the most comprehensive characterization of dental fluorosis currently available for a wild ruminant species.

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来源期刊
CiteScore
4.80
自引率
15.00%
发文量
266
审稿时长
4 months
期刊介绍: The Anatomical Record
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