11岁男孩b - all诱导的嗜酸性粒细胞增多综合征表现为急性脑病。

IF 6.2 2区医学 Q1 PEDIATRICS

Pediatrics Pub Date : 2025-04-02 DOI:10.1542/peds.2024-068064

Tristan Loveday, Cintia da Hora, Rudolph Wells, Lauren Chorny, Manisha Bansal, Scott Bradfield, Loren McLendon

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引用次数: 0

摘要

脑病是一种神经功能紊乱。它通常归因于感染性和炎症性病因，但包括广泛的差异。高嗜酸性粒细胞综合征（HES）是一种罕见的脑病的原因，是相关的潜在感染或恶性肿瘤。我们报告一位儿童患者，他经历了数天恶化的脑病和神经系统恶化，与乙型流感感染和嗜酸性粒细胞增多症有关。彻底的检查最终诊断为继发于B细胞急性淋巴细胞白血病（B- all）的HES。这个病例体现了对脑病的诊断、评估、治疗和管理保持广泛方法的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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11-Year-Old Boy With B-ALL-Induced Hypereosinophilic Syndrome Presenting as Acute Encephalopathy.

Encephalopathy is a disturbance in neurologic function. It is commonly attributed to infectious and inflammatory etiologies but encompasses a wide differential. Hypereosinophilic syndrome (HES) is a rare cause of encephalopathy that is associated with underlying infection or malignancy. We present a pediatric patient who experienced several days of worsening encephalopathy and neurological deterioration associated with influenza B infection and hypereosinophilia. A thorough workup ultimately revealed a diagnosis of HES secondary to B cell acute lymphoblastic leukemia (B-ALL). This case exemplifies the importance of maintaining a broad approach to the diagnostic evaluation, treatment, and management of encephalopathy.

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来源期刊

Pediatrics 医学-小儿科

CiteScore

12.80

自引率

5.00%

发文量

791

审稿时长

2-3 weeks

期刊介绍： The Pediatrics® journal is the official flagship journal of the American Academy of Pediatrics (AAP). It is widely cited in the field of pediatric medicine and is recognized as the leading journal in the field. The journal publishes original research and evidence-based articles, which provide authoritative information to help readers stay up-to-date with the latest developments in pediatric medicine. The content is peer-reviewed and undergoes rigorous evaluation to ensure its quality and reliability. Pediatrics also serves as a valuable resource for conducting new research studies and supporting education and training activities in the field of pediatrics. It aims to enhance the quality of pediatric outpatient and inpatient care by disseminating valuable knowledge and insights. As of 2023, Pediatrics has an impressive Journal Impact Factor (IF) Score of 8.0. The IF is a measure of a journal's influence and importance in the scientific community, with higher scores indicating a greater impact. This score reflects the significance and reach of the research published in Pediatrics, further establishing its prominence in the field of pediatric medicine.