英国获得专业过敏服务的不平等:来自BSACI免疫治疗登记处(BRIT)的报告。

IF 5.2 2区 医学 Q1 ALLERGY
Mich Erlewyn-Lajeunesse, Luciano Perfetti Villa, Shifa Shaikh, Maria Smith, Vasiliki Balodima, Sarah Baker, Tom Dawson, Pamela Ewan, Sujoy Khan, Deborah Marriage, Louise Michaelis, Leyla Pur Ozygit, Anna Thursby-Pelham, Amena Warner, Olga Maslovskaya, the BRIT Practitioners Group
{"title":"英国获得专业过敏服务的不平等:来自BSACI免疫治疗登记处(BRIT)的报告。","authors":"Mich Erlewyn-Lajeunesse,&nbsp;Luciano Perfetti Villa,&nbsp;Shifa Shaikh,&nbsp;Maria Smith,&nbsp;Vasiliki Balodima,&nbsp;Sarah Baker,&nbsp;Tom Dawson,&nbsp;Pamela Ewan,&nbsp;Sujoy Khan,&nbsp;Deborah Marriage,&nbsp;Louise Michaelis,&nbsp;Leyla Pur Ozygit,&nbsp;Anna Thursby-Pelham,&nbsp;Amena Warner,&nbsp;Olga Maslovskaya,&nbsp;the BRIT Practitioners Group","doi":"10.1111/cea.70034","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>There is an unmet need for specialist allergy treatment in the United Kingdom. Allergen immunotherapy and treatment with omalizumab for chronic spontaneous urticaria (CSU) are key markers for these services. The British Society for Allergy and Clinical Immunology (BSACI) Registry for Immunotherapy (BRIT) is a national project to record the real-world effectiveness, safety and access to treatment for aero-allergen, venom and peanut immunotherapy as well as omalizumab for CSU.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>We described participant demographics, the index of multiple deprivation (IMD) and access to treatment from the registry launch. Data for 1835 participants were available for analysis from 63 centres enrolled between 1st October 2018 and 24th August 2023.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>96.5% (1771/1835) were living in England, with only 3.5% (64) being from the devolved nations. 14.4% (251/1748) were in the most affluent IMD decile compared to 4.5% (78/1748) in the most deprived IMD decile. White participants were 1.74 times more likely to be referred directly from primary care compared to people of Asian, black, mixed or other minority ethnic groups. Instead, these groups were referred more frequently from secondary or tertiary hospital services. The median distance travelled from home to the treatment centre was 15.2 miles, with evidence of clustering around specialist centres.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>We have described disparities and unwarranted variation in the provision of treatment around the UK. The data suggest that there is limited access to immunotherapy in the devolved nations. Access is also reduced by socioeconomic deprivation. White participants were more likely to receive a direct referral from primary care than those from other ethnic groups whose referral pathways were more complex. Registry data are limited by participant enrolment and may have selection bias. Nevertheless, BRIT has highlighted inequity in access to specialist allergy services in the UK.</p>\n </section>\n </div>","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":"55 6","pages":"458-468"},"PeriodicalIF":5.2000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cea.70034","citationCount":"0","resultStr":"{\"title\":\"Inequalities in Access to Specialist Allergy Services in the United Kingdom: A Report From the BSACI Registry for Immunotherapy (BRIT)\",\"authors\":\"Mich Erlewyn-Lajeunesse,&nbsp;Luciano Perfetti Villa,&nbsp;Shifa Shaikh,&nbsp;Maria Smith,&nbsp;Vasiliki Balodima,&nbsp;Sarah Baker,&nbsp;Tom Dawson,&nbsp;Pamela Ewan,&nbsp;Sujoy Khan,&nbsp;Deborah Marriage,&nbsp;Louise Michaelis,&nbsp;Leyla Pur Ozygit,&nbsp;Anna Thursby-Pelham,&nbsp;Amena Warner,&nbsp;Olga Maslovskaya,&nbsp;the BRIT Practitioners Group\",\"doi\":\"10.1111/cea.70034\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>There is an unmet need for specialist allergy treatment in the United Kingdom. Allergen immunotherapy and treatment with omalizumab for chronic spontaneous urticaria (CSU) are key markers for these services. The British Society for Allergy and Clinical Immunology (BSACI) Registry for Immunotherapy (BRIT) is a national project to record the real-world effectiveness, safety and access to treatment for aero-allergen, venom and peanut immunotherapy as well as omalizumab for CSU.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>We described participant demographics, the index of multiple deprivation (IMD) and access to treatment from the registry launch. Data for 1835 participants were available for analysis from 63 centres enrolled between 1st October 2018 and 24th August 2023.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>96.5% (1771/1835) were living in England, with only 3.5% (64) being from the devolved nations. 14.4% (251/1748) were in the most affluent IMD decile compared to 4.5% (78/1748) in the most deprived IMD decile. White participants were 1.74 times more likely to be referred directly from primary care compared to people of Asian, black, mixed or other minority ethnic groups. Instead, these groups were referred more frequently from secondary or tertiary hospital services. The median distance travelled from home to the treatment centre was 15.2 miles, with evidence of clustering around specialist centres.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>We have described disparities and unwarranted variation in the provision of treatment around the UK. The data suggest that there is limited access to immunotherapy in the devolved nations. Access is also reduced by socioeconomic deprivation. White participants were more likely to receive a direct referral from primary care than those from other ethnic groups whose referral pathways were more complex. Registry data are limited by participant enrolment and may have selection bias. Nevertheless, BRIT has highlighted inequity in access to specialist allergy services in the UK.</p>\\n </section>\\n </div>\",\"PeriodicalId\":10207,\"journal\":{\"name\":\"Clinical and Experimental Allergy\",\"volume\":\"55 6\",\"pages\":\"458-468\"},\"PeriodicalIF\":5.2000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cea.70034\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Allergy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/cea.70034\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Allergy","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/cea.70034","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0

摘要

背景:在英国,对过敏专科治疗的需求尚未得到满足。过敏原免疫疗法和奥玛珠单抗治疗慢性自发性荨麻疹(CSU)是这些服务的关键标志。英国过敏和临床免疫学学会(BSACI)免疫疗法注册(BRIT)是一个国家项目,记录空气过敏原、蛇毒和花生免疫疗法以及奥玛珠单抗治疗CSU的实际有效性、安全性和可及性。方法:我们描述了参与者的人口统计数据,多重剥夺指数(IMD)和获得治疗的机会。2018年10月1日至2023年8月24日期间,来自63个中心的1835名参与者的数据可供分析。结果:96.5%(1771/1835)居住在英格兰,只有3.5%(64)来自下放国家。14.4%(251/1748)处于最富裕的IMD十分位数,而4.5%(78/1748)处于最贫困的IMD十分位数。与亚裔、黑人、混血儿或其他少数族裔人群相比,白人参与者直接从初级保健转介的可能性要高1.74倍。相反,这些群体更频繁地从二级或三级医院转诊。从家到治疗中心的中间距离为15.2英里,有证据表明专科中心周围聚集。结论:我们描述了在英国各地提供治疗的差异和无根据的变化。数据表明,在权力下放的国家,获得免疫治疗的机会有限。社会经济剥夺也减少了获取机会。与转诊途径更为复杂的其他种族相比,白人参与者更有可能接受初级保健的直接转诊。注册数据受参与者登记的限制,可能存在选择偏倚。然而,BRIT强调了在英国获得专业过敏服务的不平等。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Inequalities in Access to Specialist Allergy Services in the United Kingdom: A Report From the BSACI Registry for Immunotherapy (BRIT)

Inequalities in Access to Specialist Allergy Services in the United Kingdom: A Report From the BSACI Registry for Immunotherapy (BRIT)

Background

There is an unmet need for specialist allergy treatment in the United Kingdom. Allergen immunotherapy and treatment with omalizumab for chronic spontaneous urticaria (CSU) are key markers for these services. The British Society for Allergy and Clinical Immunology (BSACI) Registry for Immunotherapy (BRIT) is a national project to record the real-world effectiveness, safety and access to treatment for aero-allergen, venom and peanut immunotherapy as well as omalizumab for CSU.

Methods

We described participant demographics, the index of multiple deprivation (IMD) and access to treatment from the registry launch. Data for 1835 participants were available for analysis from 63 centres enrolled between 1st October 2018 and 24th August 2023.

Results

96.5% (1771/1835) were living in England, with only 3.5% (64) being from the devolved nations. 14.4% (251/1748) were in the most affluent IMD decile compared to 4.5% (78/1748) in the most deprived IMD decile. White participants were 1.74 times more likely to be referred directly from primary care compared to people of Asian, black, mixed or other minority ethnic groups. Instead, these groups were referred more frequently from secondary or tertiary hospital services. The median distance travelled from home to the treatment centre was 15.2 miles, with evidence of clustering around specialist centres.

Conclusions

We have described disparities and unwarranted variation in the provision of treatment around the UK. The data suggest that there is limited access to immunotherapy in the devolved nations. Access is also reduced by socioeconomic deprivation. White participants were more likely to receive a direct referral from primary care than those from other ethnic groups whose referral pathways were more complex. Registry data are limited by participant enrolment and may have selection bias. Nevertheless, BRIT has highlighted inequity in access to specialist allergy services in the UK.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
10.40
自引率
9.80%
发文量
189
审稿时长
3-8 weeks
期刊介绍: Clinical & Experimental Allergy strikes an excellent balance between clinical and scientific articles and carries regular reviews and editorials written by leading authorities in their field. In response to the increasing number of quality submissions, since 1996 the journals size has increased by over 30%. Clinical & Experimental Allergy is essential reading for allergy practitioners and research scientists with an interest in allergic diseases and mechanisms. Truly international in appeal, Clinical & Experimental Allergy publishes clinical and experimental observations in disease in all fields of medicine in which allergic hypersensitivity plays a part.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信