从萨斯喀彻温省萨斯卡通西部兽医学院接收的马匹中分离出的大肠埃希菌抗菌药敏感性调查。

IF 0.9 4区 农林科学 Q3 VETERINARY SCIENCES
Maria C Polo, Florence D Huby, Fabienne D Uehlinger, Joseph E Rubin
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引用次数: 0

摘要

目的:抗微生物药物耐药性是人类和兽医学面临的严重威胁。最有问题的耐药生物是产生广谱β-内酰胺酶(ESBL)的肠杆菌,它对第三代头孢菌素具有耐药性。本研究的目的是确定西部兽医学院录取的马中耐药大肠杆菌的定植频率。动物和手术:从2021年11月至2022年3月收治的60匹马身上收集直肠拭子。拭子选择性培养大肠杆菌,用标准生化试验鉴定。对分离株进行药敏检测,并采用PCR方法筛选耐药菌株。结果:60匹马均分离到大肠杆菌。虽然全敏感是最常见的表型,但从1匹马中发现了具有ctx - m型ESBL的多重耐药分离株。甲氧苄啶+磺胺甲恶唑耐药是最常见的耐药表型。结论和临床意义:尽管耐药性并不常见,但鉴定出产生esbl的分离株强调了继续监测以监测马种群中耐药性出现的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Survey of the antimicrobial susceptibility of Escherichia coli isolated from horses admitted to the Western College of Veterinary Medicine, Saskatoon, Saskatchewan.

Objective: Antimicrobial resistance is a serious threat in human and veterinary medicine. Among the most problematic resistant organisms are the extended-spectrum β-lactamase (ESBL)-producing Enterobacterales, which are resistant to the 3rd-generation cephalosporins. The purpose of this study was to determine the frequency of colonization of horses admitted to the Western College of Veterinary Medicine with resistant Escherichia coli.

Animals and procedure: Rectal swabs were collected from 60 horses admitted between November 2021 and March 2022. Swabs were selectively cultured for E. coli, which was identified using standard biochemical tests. The antimicrobial susceptibility of isolates was determined, and resistant isolates were screened using PCR for the presence of ESBL.

Results: Escherichia coli was isolated from all 60 horses. Although pansusceptibility was the most commonly identified phenotype, multidrug-resistant isolates possessing a CTX-M-type ESBL were recovered from 1 horse. Resistance to trimethoprim + sulfamethoxazole was the most commonly encountered resistant phenotype.

Conclusion and clinical relevance: Although resistance was uncommon, the identification of ESBL-producing isolates highlighted the importance of continued surveillance to monitor the emergence of resistance in equine populations.

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来源期刊
CiteScore
1.20
自引率
10.00%
发文量
177
审稿时长
12-24 weeks
期刊介绍: The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health. A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).
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