沙门氏菌是胆囊癌和结肠癌的潜在元凶

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2025-04-02 DOI:10.1038/s41568-025-00812-z

Virginie Stévenin, Jacques Neefjes

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引用次数: 0

摘要

沙门氏菌每年感染数亿人，入侵宿主细胞并改变可能促进癌症的信号通路。由于其生物学起源，沙门氏菌诱导的癌症可能对特定治疗有更好的反应，从而揭示细菌驱动的细胞转化的不同模式以及对抗它们的有效方法。沙门氏菌感染在全球普遍存在，与癌症风险增加有关，尤其是胆囊癌和结肠癌。在这篇评论中，stsamuvenin和Neefjes强调有必要进一步研究沙门氏菌驱动的细胞转化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Salmonella, the insidious contributor to gallbladder and colon cancers

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Salmonella, the insidious contributor to gallbladder and colon cancers

Salmonella infects hundreds of millions of people yearly, invading host cells and altering signalling pathways that can promote cancer. Owing to their biological origin, Salmonella-induced cancers may respond better to specific treatments, shedding light on different modes of bacterially driven cellular transformation and effective ways to counter them. Salmonella infections, prevalent globally, correlate with increased risk of cancer, particularly gallbladder and colon cancers. In this Comment, Stévenin and Neefjes highlight the need for further investigation into Salmonella-driven cellular transformation.

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.