成人视网膜母细胞瘤:两例罕见病例报告。

Mymensingh medical journal : MMJ Pub Date : 2025-04-01
S R Roy, F Huque, M Nuruddin
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摘要

成人视网膜母细胞瘤是一种罕见的发现,经常引起诊断困境。我们报告的两例患者年龄分别为20岁和40岁,均为男性。两例均表现为单侧视力丧失,无阳性家族史。第1例临床检查显示模糊玻璃体内白色肿块伴虹膜新生血管形成及眼压升高。第二例眼底扩张检查显示白色视网膜肿块升高,伴输水血管。两例均以长视神经摘除术为主。组织病理学证实视网膜母细胞瘤的诊断为成人发病,与组织病理学高危因素无关。视网膜母细胞瘤是一种毁灭性的疾病,在成人视网膜无色素变性病变中,医生必须高度警惕,排除视网膜母细胞瘤的可能性,以挽救生命。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adult Onset Retinoblastoma: Two Rare Case Reports.

Retinoblastoma in adult is one of rarer findings and always causing a diagnostic dilemma. Our two reported cases were 20 and 40 years old and both were male. Both cases presented with unilateral vision loss and without any positive family history. Clinical examination of the first case revealed whitish mass in hazy vitreous along with neovascularization of iris and raised intraocular pressure. In second case, dilated fundus examination showed elevated whitish retinal mass with feeder vessel. Both cases were diagnosed mostly clinically and surgically managed by enucleation with long optic nerve. Histopathology confirmed the diagnosis of retinoblastoma of adult onset and was not associated with histopathological high risk factors. Physician's high suspicion is needed to rule out retinoblastoma in any amelanotic retinal lesions in adult to save life as retinoblastoma is a devastating disease.

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