胃液分析在临床实践中的应用:准备好了吗?

IF 1.9 Q3 GASTROENTEROLOGY & HEPATOLOGY
Emanuele Dilaghi, Gianluca Esposito, Gianluca Franchellucci, Bruno Annibale, Angelo Zullo
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引用次数: 0

摘要

幽门螺杆菌(h.p ylori)感染是最常见的胃十二指肠疾病和胃萎缩的主要原因,伴或不伴肠化生,易发生胃癌。胃液分析可能有助于诊断这些疾病,通过测量铵浓度和pH水平揭示幽门螺杆菌感染和低氯酸血症状态。EndoFaster®是一种用于对胃液进行实时分析的设备。现有数据显示,在排除感染和萎缩性胃炎方面具有很高的阴性预测值,因此当检测结果为阴性时,可能减少对胃活检的需要。本综述旨在评估EndoFaster®在支持幽门螺杆菌感染诊断、检测胃癌前病变和其他特定临床应用方面的潜在作用,潜在地减少不必要的胃活检。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gastric juice analysis in clinical practice: are we ready for the prime time?

Helicobacter pylori (H. pylori) infection is the main cause of the most frequent gastroduodenal diseases and gastric atrophy, with or without intestinal metaplasia, which predisposes to gastric cancer development. Gastric juice analysis may be useful in diagnosing these conditions, revealing the H. pylori infection and hypochlorhydria status by measuring ammonium concentrations and pH levels. EndoFaster® is a device introduced to perform these analyses on gastric juice in real-time. The available data showed very high negative predictive values in ruling out the infection and corpus atrophic gastritis, thereby potentially reducing the need for gastric biopsies when test results are negative. This review aims to assess the potential role of EndoFaster® in supporting the diagnosis of H. pylori infection, detecting gastric precancerous lesions, and other specific clinical applications, potentially reducing unnecessary gastric biopsies.

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