Ting Ting Dai, Ting Xu, Qi Ling Wang, Hao Bo Ni, Chun Ying Song, Yu Shan Li, Fu Ping Li, Tian Qing Meng, Hui Qiang Sheng, Ling Xi Wang, Xiao Yan Cai, Li Na Xiao, Xiao Lin Yu, Qing Hui Zeng, Pi Guo, Xin Zong Zhang
{"title":"热夜暴露对人类精液质量的影响：一项多中心人群研究。","authors":"Ting Ting Dai, Ting Xu, Qi Ling Wang, Hao Bo Ni, Chun Ying Song, Yu Shan Li, Fu Ping Li, Tian Qing Meng, Hui Qiang Sheng, Ling Xi Wang, Xiao Yan Cai, Li Na Xiao, Xiao Lin Yu, Qing Hui Zeng, Pi Guo, Xin Zong Zhang","doi":"10.3967/bes2024.131","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To explore and quantify the association of hot night exposure during the sperm development period (0-90 lag days) with semen quality.</p><p><strong>Methods: </strong>A total of 6,640 male sperm donors from 6 human sperm banks in China during 2014-2020 were recruited in this multicenter study. Two indices (i.e., hot night excess [HNE] and hot night duration [HND]) were used to estimate the heat intensity and duration during nighttime. Linear mixed models were used to examine the association between hot nights and semen quality parameters.</p><p><strong>Results: </strong>The exposure-response relationship revealed that HNE and HND during 0-90 days before semen collection had a significantly inverse association with sperm motility. Specifically, a 1 °C increase in HNE was associated with decreased sperm progressive motility of 0.0090 (95% confidence interval [ <i>CI</i>]: -0.0147, -0.0033) and decreased total motility of 0.0094 (95% <i>CI</i>: -0.0160, -0.0029). HND was significantly associated with reduced sperm progressive motility and total motility of 0.0021 (95% <i>CI</i>: -0.0040, -0.0003) and 0.0023 (95% <i>CI</i>: -0.0043, -0.0002), respectively. Consistent results were observed at different temperature thresholds on hot nights.</p><p><strong>Conclusion: </strong>Our findings highlight the need to mitigate nocturnal heat exposure during spermatogenesis to maintain optimal semen quality.</p>","PeriodicalId":93903,"journal":{"name":"Biomedical and environmental sciences : BES","volume":"38 2","pages":"178-193"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of Hot Night Exposure on Human Semen Quality: A Multicenter Population-Based Study.\",\"authors\":\"Ting Ting Dai, Ting Xu, Qi Ling Wang, Hao Bo Ni, Chun Ying Song, Yu Shan Li, Fu Ping Li, Tian Qing Meng, Hui Qiang Sheng, Ling Xi Wang, Xiao Yan Cai, Li Na Xiao, Xiao Lin Yu, Qing Hui Zeng, Pi Guo, Xin Zong Zhang\",\"doi\":\"10.3967/bes2024.131\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To explore and quantify the association of hot night exposure during the sperm development period (0-90 lag days) with semen quality.</p><p><strong>Methods: </strong>A total of 6,640 male sperm donors from 6 human sperm banks in China during 2014-2020 were recruited in this multicenter study. Two indices (i.e., hot night excess [HNE] and hot night duration [HND]) were used to estimate the heat intensity and duration during nighttime. Linear mixed models were used to examine the association between hot nights and semen quality parameters.</p><p><strong>Results: </strong>The exposure-response relationship revealed that HNE and HND during 0-90 days before semen collection had a significantly inverse association with sperm motility. Specifically, a 1 °C increase in HNE was associated with decreased sperm progressive motility of 0.0090 (95% confidence interval [ <i>CI</i>]: -0.0147, -0.0033) and decreased total motility of 0.0094 (95% <i>CI</i>: -0.0160, -0.0029). HND was significantly associated with reduced sperm progressive motility and total motility of 0.0021 (95% <i>CI</i>: -0.0040, -0.0003) and 0.0023 (95% <i>CI</i>: -0.0043, -0.0002), respectively. Consistent results were observed at different temperature thresholds on hot nights.</p><p><strong>Conclusion: </strong>Our findings highlight the need to mitigate nocturnal heat exposure during spermatogenesis to maintain optimal semen quality.</p>\",\"PeriodicalId\":93903,\"journal\":{\"name\":\"Biomedical and environmental sciences : BES\",\"volume\":\"38 2\",\"pages\":\"178-193\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical and environmental sciences : BES\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3967/bes2024.131\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical and environmental sciences : BES","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3967/bes2024.131","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of Hot Night Exposure on Human Semen Quality: A Multicenter Population-Based Study.
Objective: To explore and quantify the association of hot night exposure during the sperm development period (0-90 lag days) with semen quality.
Methods: A total of 6,640 male sperm donors from 6 human sperm banks in China during 2014-2020 were recruited in this multicenter study. Two indices (i.e., hot night excess [HNE] and hot night duration [HND]) were used to estimate the heat intensity and duration during nighttime. Linear mixed models were used to examine the association between hot nights and semen quality parameters.
Results: The exposure-response relationship revealed that HNE and HND during 0-90 days before semen collection had a significantly inverse association with sperm motility. Specifically, a 1 °C increase in HNE was associated with decreased sperm progressive motility of 0.0090 (95% confidence interval [ CI]: -0.0147, -0.0033) and decreased total motility of 0.0094 (95% CI: -0.0160, -0.0029). HND was significantly associated with reduced sperm progressive motility and total motility of 0.0021 (95% CI: -0.0040, -0.0003) and 0.0023 (95% CI: -0.0043, -0.0002), respectively. Consistent results were observed at different temperature thresholds on hot nights.
Conclusion: Our findings highlight the need to mitigate nocturnal heat exposure during spermatogenesis to maintain optimal semen quality.
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